Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer

Niramol Savaraj, Rong Xu, Howard Landy, Shenghan Lai, Linda Sternau, Jeannine Solomon, Chun Jing Wu, Theodore Lampidis, Lynn G. Feun

Research output: Contribution to journalArticle

Abstract

Topoisomerase I (TOP I) and II (TOP II) activities and their corresponding levels were analyzed in 27 primary brain tumors and 32 lung cancers (28 NSCLC, 4 SCLC). The TOP I and II activities in primary brain tumors varied from 500-2,000 units/mg and 100-3,000 units/mg respectively. Their corresponding levels varied from 2=0.2 and p

Original languageEnglish (US)
Pages (from-to)857-861
Number of pages5
JournalOncology Reports
Volume4
Issue number4
StatePublished - Jul 1997
Externally publishedYes

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Type II DNA Topoisomerase
Type I DNA Topoisomerase
Brain Neoplasms
Lung Neoplasms

Keywords

  • Brain tumor
  • Lung cancer
  • Topoisomerase I and II

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Savaraj, N., Xu, R., Landy, H., Lai, S., Sternau, L., Solomon, J., ... Feun, L. G. (1997). Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer. Oncology Reports, 4(4), 857-861.

Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer. / Savaraj, Niramol; Xu, Rong; Landy, Howard; Lai, Shenghan; Sternau, Linda; Solomon, Jeannine; Wu, Chun Jing; Lampidis, Theodore; Feun, Lynn G.

In: Oncology Reports, Vol. 4, No. 4, 07.1997, p. 857-861.

Research output: Contribution to journalArticle

Savaraj, N, Xu, R, Landy, H, Lai, S, Sternau, L, Solomon, J, Wu, CJ, Lampidis, T & Feun, LG 1997, 'Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer', Oncology Reports, vol. 4, no. 4, pp. 857-861.
Savaraj N, Xu R, Landy H, Lai S, Sternau L, Solomon J et al. Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer. Oncology Reports. 1997 Jul;4(4):857-861.
Savaraj, Niramol ; Xu, Rong ; Landy, Howard ; Lai, Shenghan ; Sternau, Linda ; Solomon, Jeannine ; Wu, Chun Jing ; Lampidis, Theodore ; Feun, Lynn G. / Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer. In: Oncology Reports. 1997 ; Vol. 4, No. 4. pp. 857-861.
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