Comparison of three societally derived health-state classification values among older African Americans with depressive symptoms

Eric Jutkowitz, Laura Pizzi, Edward Hess, Dong Churl Suh, Laura N Gitlin

Research output: Contribution to journalArticle

Abstract

Purpose: To compare societal values across three health-state classification systems in older African Americans with depression and to describe the association of these instruments to depression severity. Methods: We summarized baseline values for EQ-5D (US weights) and HUI2/3 (Canadian weights) and their subscales for 118 older African American participants enrolled in a randomized depression treatment trial and calculated correlations between the different instruments. We evaluated ceiling and floor effects for each instrument by comparing the proportion at the highest and lowest possible score for each tool. Also, utility scores were assessed by level of depression severity (mild, moderate, moderate severe, severe) scores as measured by the Patient Health Questionnaire (PHQ-9). Results: Mean utility values were 0.58 (SD = 0.21) for EQ-5D, 0.52 (SD = 0.21) for HUI2, and 0.36 (SD = 0.31) for HUI3. For the EQ-5D, 72 % of participants reported having some problems on the anxiety/depression domain. On the emotion domain for the HUI2, 23 % reported the highest level of impairment compared to only 3 % on the HUI3. No participant scored at the floor for the EQ-5D, HUI2, or HUI3 index; one participant scored at the ceiling value on the HUI3 index. Correlations ranged from 0.63 to 0.82 (all of which were significant at an alpha level of 0.05). In general, utility scores trended inversely with depression level. Conclusion: Small differences in the three preference-weighted health-state classification systems were evident for this sample of older African Americans with depressive symptoms, with HUI scores lower than EQ-5D. For this sample, utility scores were lower (i.e.; poorer) than the general United States population with depression on each utility measure.

Original languageEnglish (US)
Pages (from-to)1491-1498
Number of pages8
JournalQuality of Life Research
Volume22
Issue number6
DOIs
StatePublished - Aug 2013

Fingerprint

African Americans
Depression
Health
Weights and Measures
Emotions
Anxiety
Population

Keywords

  • Cost-effectiveness analysis
  • EQ-5D
  • HUI3
  • Quality of life
  • Utility

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Medicine(all)

Cite this

Comparison of three societally derived health-state classification values among older African Americans with depressive symptoms. / Jutkowitz, Eric; Pizzi, Laura; Hess, Edward; Suh, Dong Churl; Gitlin, Laura N.

In: Quality of Life Research, Vol. 22, No. 6, 08.2013, p. 1491-1498.

Research output: Contribution to journalArticle

@article{c88027eafbde47799a150c7ae37a192b,
title = "Comparison of three societally derived health-state classification values among older African Americans with depressive symptoms",
abstract = "Purpose: To compare societal values across three health-state classification systems in older African Americans with depression and to describe the association of these instruments to depression severity. Methods: We summarized baseline values for EQ-5D (US weights) and HUI2/3 (Canadian weights) and their subscales for 118 older African American participants enrolled in a randomized depression treatment trial and calculated correlations between the different instruments. We evaluated ceiling and floor effects for each instrument by comparing the proportion at the highest and lowest possible score for each tool. Also, utility scores were assessed by level of depression severity (mild, moderate, moderate severe, severe) scores as measured by the Patient Health Questionnaire (PHQ-9). Results: Mean utility values were 0.58 (SD = 0.21) for EQ-5D, 0.52 (SD = 0.21) for HUI2, and 0.36 (SD = 0.31) for HUI3. For the EQ-5D, 72 {\%} of participants reported having some problems on the anxiety/depression domain. On the emotion domain for the HUI2, 23 {\%} reported the highest level of impairment compared to only 3 {\%} on the HUI3. No participant scored at the floor for the EQ-5D, HUI2, or HUI3 index; one participant scored at the ceiling value on the HUI3 index. Correlations ranged from 0.63 to 0.82 (all of which were significant at an alpha level of 0.05). In general, utility scores trended inversely with depression level. Conclusion: Small differences in the three preference-weighted health-state classification systems were evident for this sample of older African Americans with depressive symptoms, with HUI scores lower than EQ-5D. For this sample, utility scores were lower (i.e.; poorer) than the general United States population with depression on each utility measure.",
keywords = "Cost-effectiveness analysis, EQ-5D, HUI3, Quality of life, Utility",
author = "Eric Jutkowitz and Laura Pizzi and Edward Hess and Suh, {Dong Churl} and Gitlin, {Laura N}",
year = "2013",
month = "8",
doi = "10.1007/s11136-012-0263-y",
language = "English (US)",
volume = "22",
pages = "1491--1498",
journal = "Quality of Life Research",
issn = "0962-9343",
publisher = "Springer Netherlands",
number = "6",

}

TY - JOUR

T1 - Comparison of three societally derived health-state classification values among older African Americans with depressive symptoms

AU - Jutkowitz, Eric

AU - Pizzi, Laura

AU - Hess, Edward

AU - Suh, Dong Churl

AU - Gitlin, Laura N

PY - 2013/8

Y1 - 2013/8

N2 - Purpose: To compare societal values across three health-state classification systems in older African Americans with depression and to describe the association of these instruments to depression severity. Methods: We summarized baseline values for EQ-5D (US weights) and HUI2/3 (Canadian weights) and their subscales for 118 older African American participants enrolled in a randomized depression treatment trial and calculated correlations between the different instruments. We evaluated ceiling and floor effects for each instrument by comparing the proportion at the highest and lowest possible score for each tool. Also, utility scores were assessed by level of depression severity (mild, moderate, moderate severe, severe) scores as measured by the Patient Health Questionnaire (PHQ-9). Results: Mean utility values were 0.58 (SD = 0.21) for EQ-5D, 0.52 (SD = 0.21) for HUI2, and 0.36 (SD = 0.31) for HUI3. For the EQ-5D, 72 % of participants reported having some problems on the anxiety/depression domain. On the emotion domain for the HUI2, 23 % reported the highest level of impairment compared to only 3 % on the HUI3. No participant scored at the floor for the EQ-5D, HUI2, or HUI3 index; one participant scored at the ceiling value on the HUI3 index. Correlations ranged from 0.63 to 0.82 (all of which were significant at an alpha level of 0.05). In general, utility scores trended inversely with depression level. Conclusion: Small differences in the three preference-weighted health-state classification systems were evident for this sample of older African Americans with depressive symptoms, with HUI scores lower than EQ-5D. For this sample, utility scores were lower (i.e.; poorer) than the general United States population with depression on each utility measure.

AB - Purpose: To compare societal values across three health-state classification systems in older African Americans with depression and to describe the association of these instruments to depression severity. Methods: We summarized baseline values for EQ-5D (US weights) and HUI2/3 (Canadian weights) and their subscales for 118 older African American participants enrolled in a randomized depression treatment trial and calculated correlations between the different instruments. We evaluated ceiling and floor effects for each instrument by comparing the proportion at the highest and lowest possible score for each tool. Also, utility scores were assessed by level of depression severity (mild, moderate, moderate severe, severe) scores as measured by the Patient Health Questionnaire (PHQ-9). Results: Mean utility values were 0.58 (SD = 0.21) for EQ-5D, 0.52 (SD = 0.21) for HUI2, and 0.36 (SD = 0.31) for HUI3. For the EQ-5D, 72 % of participants reported having some problems on the anxiety/depression domain. On the emotion domain for the HUI2, 23 % reported the highest level of impairment compared to only 3 % on the HUI3. No participant scored at the floor for the EQ-5D, HUI2, or HUI3 index; one participant scored at the ceiling value on the HUI3 index. Correlations ranged from 0.63 to 0.82 (all of which were significant at an alpha level of 0.05). In general, utility scores trended inversely with depression level. Conclusion: Small differences in the three preference-weighted health-state classification systems were evident for this sample of older African Americans with depressive symptoms, with HUI scores lower than EQ-5D. For this sample, utility scores were lower (i.e.; poorer) than the general United States population with depression on each utility measure.

KW - Cost-effectiveness analysis

KW - EQ-5D

KW - HUI3

KW - Quality of life

KW - Utility

UR - http://www.scopus.com/inward/record.url?scp=84885187739&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885187739&partnerID=8YFLogxK

U2 - 10.1007/s11136-012-0263-y

DO - 10.1007/s11136-012-0263-y

M3 - Article

C2 - 22972437

AN - SCOPUS:84885187739

VL - 22

SP - 1491

EP - 1498

JO - Quality of Life Research

JF - Quality of Life Research

SN - 0962-9343

IS - 6

ER -