The effects of sample volatility, proton affinity, and charge on the mass spectra produced by the fast atom bombardment and thermospray Ionization techniques are compared. In general, the thermospray technique produced comparatively more fragmentation, while the dependence on sample proton affinity In the presence of ammonium acetate buffer Is similar In both techniques. Doubly charged Ions are more often formed in thermospray and may reflect differences In the Ion formation mechanisms.
ASJC Scopus subject areas
- Analytical Chemistry