Comparison of the Hypnotic Effectiveness of Secobarbital, Pentobarbital, Methyprylon and Ethchlorvynol

JOSEPH H. PATTISON, RICHARD P. ALLEN

Research output: Contribution to journalArticle

Abstract

ABSTRACT: A double‐blind placebo‐controlled study was made of the hypnotic effects of secobarbital (100 mg), pentobarbital (100 mg), methyprylon (Noludar) (300 mg), and ethchlorvynol (Placidyl) (500 mg) in 50 patients in a chronic disease hospital. The criteria included sleep onset and sleep duration (in half‐hour units). Pentobarbital, methyprylon, and secobarbital were clearly superior to placebo, and pentobarbital was consistently the best. Methyprylon seemed slightly better than secobarbital. In elderly or chronically ill patients for whom administration of barbiturates is considered too risky, methyprylon is an alternative effective hypnotic for simple insomnia. 1972 The American Geriatrics Society

Original languageEnglish (US)
Pages (from-to)398-402
Number of pages5
JournalJournal of the American Geriatrics Society
Volume20
Issue number8
DOIs
StatePublished - Aug 1972

    Fingerprint

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this