Comparison of the Denka-Seiken INFLU A·B-Quick and BD Directigen Flu A+B kits with direct fluorescent-antibody staining and shell vial culture methods for rapid detection of influenza viruses

James J. Dunn, Chris Gordon, Christy Kelley, Karen C. Carroll

Research output: Contribution to journalArticlepeer-review

Abstract

The INFLU A·B-Quick and Directigen Flu A+B enzyme immunoassays were compared with direct immunofluorescence and cell culture for detection of influenza A and B viruses in a total of 255 patient specimens. Both assays identified 23 of 42 influenza A viruses (sensitivity, 54.8%; specificity, 100%; positive predictive value [PPV], 100%; negative predictive value [NPV], 91.8%). The INFLU A·B-Quick assay identified 10 of 16 influenza B viruses (sensitivity, 62.5%; specificity, 99.6%; PPV, 90.9%; NPV, 97.5%), and the Directigen Flu A+B assay detected 9 of 16 influenza B viruses (sensitivity, 56.3%; specificity, 99.6%; PPV, 90%; NPV, 97.1%).

Original languageEnglish (US)
Pages (from-to)2180-2183
Number of pages4
JournalJournal of clinical microbiology
Volume41
Issue number5
DOIs
StatePublished - May 1 2003

ASJC Scopus subject areas

  • Microbiology (medical)

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