TY - JOUR
T1 - Comparison of the Denka-Seiken INFLU A·B-Quick and BD Directigen Flu A+B kits with direct fluorescent-antibody staining and shell vial culture methods for rapid detection of influenza viruses
AU - Dunn, James J.
AU - Gordon, Chris
AU - Kelley, Christy
AU - Carroll, Karen C.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - The INFLU A·B-Quick and Directigen Flu A+B enzyme immunoassays were compared with direct immunofluorescence and cell culture for detection of influenza A and B viruses in a total of 255 patient specimens. Both assays identified 23 of 42 influenza A viruses (sensitivity, 54.8%; specificity, 100%; positive predictive value [PPV], 100%; negative predictive value [NPV], 91.8%). The INFLU A·B-Quick assay identified 10 of 16 influenza B viruses (sensitivity, 62.5%; specificity, 99.6%; PPV, 90.9%; NPV, 97.5%), and the Directigen Flu A+B assay detected 9 of 16 influenza B viruses (sensitivity, 56.3%; specificity, 99.6%; PPV, 90%; NPV, 97.1%).
AB - The INFLU A·B-Quick and Directigen Flu A+B enzyme immunoassays were compared with direct immunofluorescence and cell culture for detection of influenza A and B viruses in a total of 255 patient specimens. Both assays identified 23 of 42 influenza A viruses (sensitivity, 54.8%; specificity, 100%; positive predictive value [PPV], 100%; negative predictive value [NPV], 91.8%). The INFLU A·B-Quick assay identified 10 of 16 influenza B viruses (sensitivity, 62.5%; specificity, 99.6%; PPV, 90.9%; NPV, 97.5%), and the Directigen Flu A+B assay detected 9 of 16 influenza B viruses (sensitivity, 56.3%; specificity, 99.6%; PPV, 90%; NPV, 97.1%).
UR - http://www.scopus.com/inward/record.url?scp=0037951718&partnerID=8YFLogxK
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U2 - 10.1128/JCM.41.5.2180-2183.2003
DO - 10.1128/JCM.41.5.2180-2183.2003
M3 - Article
C2 - 12734274
AN - SCOPUS:0037951718
SN - 0095-1137
VL - 41
SP - 2180
EP - 2183
JO - Journal of clinical microbiology
JF - Journal of clinical microbiology
IS - 5
ER -