Comparison of the Cepheid GeneXpert CT/NG assay to the Hologic Aptima Combo2 assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in self-collected rectal swabs

Laura Dize; Barbara Silver; Charlotte Gaydos

doi:10.1016/j.diagmicrobio.2017.10.013

Comparison of the Cepheid GeneXpert CT/NG assay to the Hologic Aptima Combo2 assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in self-collected rectal swabs

Laura Dize, Barbara Silver, Charlotte Gaydos

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Self-collected rectal-swabs were tested for CT and NG on GeneXpert CT/NG as compared to APTIMA Combo2. Of 448 rectal-swabs, 22 were positive for CT; 7 for NG on both assays; two were discordant. Sensitivity and specificity of GeneXpert was 95.5% and 99.7% for chlamydia, respectively; for gonorrhea both were 100%.

Original language	English (US)
Pages (from-to)	83-84
Number of pages	2
Journal	Diagnostic Microbiology and Infectious Disease
Volume	90
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2017.10.013
State	Published - Feb 2018

Keywords

Chlamydia
Gonorrhea
NAATs
Rectal swabs

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.diagmicrobio.2017.10.013

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Comparison of the Cepheid GeneXpert CT/NG assay to the Hologic Aptima Combo2 assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in self-collected rectal swabs. / Dize, Laura; Silver, Barbara; Gaydos, Charlotte.

In: Diagnostic Microbiology and Infectious Disease, Vol. 90, No. 2, 02.2018, p. 83-84.

Research output: Contribution to journal › Article › peer-review

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