Comparison of the abbott m2000 realtime CT assay and the cepheid genexpert CT/NG assay to the roche amplicor CT assay for detection of chlamydia trachomatis in ocular samples from Tanzania

Laura Dize, Sheila West, James A. Williams, Barbara Van Der Pol, Thomas C. Quinn, Charlotte A. Gaydos

Research output: Contribution to journalArticle

Abstract

The GeneXpert CT/NG assay (GeneXpert) and the Abbottm2000 RealTime CT (m2000) assay were compared to Amplicor for detecting ocular Chlamydia trachomatis. Discordant specimens were tested by the Aptima CT assay. The m2000 assay sensitivity was 100% (95% confidence interval [CI], 90% to 100%), and specificity was 98.46% (95% CI, 95.2% to 99.2%); GeneXpert sensitivity was 100% (95% CI, 90% to 100%), and specificity was 100% (95% CI, 98.1% to 100%). The m2000 and GeneXpert assays appear to perform as well as the Amplicor assay.

Original languageEnglish (US)
Pages (from-to)1611-1613
Number of pages3
JournalJournal of clinical microbiology
Volume51
Issue number5
DOIs
StatePublished - May 2013

ASJC Scopus subject areas

  • Microbiology (medical)

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