TY - JOUR
T1 - Comparison of Sucrose and Glucose in the Oral Electrolyte Therapy of Cholera and Other Severe Diarrheas
AU - Palmer, Darwin L.
AU - Koster, F. T.
AU - Islam, A. F.M.Rafiqul
AU - Rahman, A. S.M.Mizanur
AU - Sack, R. Bradley
PY - 1977/11/17
Y1 - 1977/11/17
N2 - Oral glucose electrolyte solution is now established as simple, effective and relatively inexpensive fluid-replacement therapy1 2 3 4 5 for severe diarrheal disease, the leading cause of morbidity in the developing world. Cholera, the illness with most massive stool loss, has been treated successfully with oral solution in the hospital as well as in the field situation,67 and in children8 9 10 as well as in adults. The electrolyte components (table salt, sodium bicarbonate and a potassium salt) are cheap, available and easily stored. Glucose, which is necessary to promote intestinal absorption of sodium and concomitantly of water,11 is relatively expensive and may not be available.
AB - Oral glucose electrolyte solution is now established as simple, effective and relatively inexpensive fluid-replacement therapy1 2 3 4 5 for severe diarrheal disease, the leading cause of morbidity in the developing world. Cholera, the illness with most massive stool loss, has been treated successfully with oral solution in the hospital as well as in the field situation,67 and in children8 9 10 as well as in adults. The electrolyte components (table salt, sodium bicarbonate and a potassium salt) are cheap, available and easily stored. Glucose, which is necessary to promote intestinal absorption of sodium and concomitantly of water,11 is relatively expensive and may not be available.
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U2 - 10.1056/NEJM197711172972007
DO - 10.1056/NEJM197711172972007
M3 - Article
C2 - 333291
AN - SCOPUS:0017760455
SN - 0028-4793
VL - 297
SP - 1107
EP - 1110
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 20
ER -