Comparison of standard and Quadruple-Phase contrast Material injection for artifacts, image Quality, and radiation Dose in the evaluation of head and neck cancer Metastases

Charbel Saade, Fadi El-Merhi, Ahmad Mayat, Patrick C. Brennan, David Mark Yousem

Research output: Contribution to journalArticle

Abstract

Purpose: To investigate opacification of head and neck vasculature during computed tomography (CT) of supraclavicular lymph nodes with a quadruple-phase contrast media and saline dual-injection protocol. Materials and Methods: This retrospective study was institutional review board approved. In 180 consecutive patients, routine head and neck CT was performed with one of two protocols: protocol A, craniocaudal scan direction with 100 mL of contrast material injected intravenously as a single bolus; or protocol B, 100 mL of contrast material injected in four phases (phases 1-2, 60 mL of contrast material and saline injected at 2.5 mL/sec; phases 3-4, 40 mL of contrast material and saline injected at 2.5 mL/sec); both protocols had a fixed scan delay of 70 seconds. Attenuation of supraclavicular arteries and veins was measured with arteriovenous contrast ratio (AVCR) and contrast-to-noise ratio (CNR). Effective dose was calculated. Data were compared with the two-sample t test. Receiver operating characteristic (ROC) and visual grading characteristic analyses were performed. Results: Arterial attenuation was up to 20% higher (P

Original languageEnglish (US)
Pages (from-to)571-577
Number of pages7
JournalRadiology
Volume279
Issue number2
DOIs
StatePublished - May 1 2016

Fingerprint

Head and Neck Neoplasms
Artifacts
Contrast Media
Radiation
Neoplasm Metastasis
Injections
Neck
Head
Tomography
Research Ethics Committees
ROC Curve
Noise
Veins
Retrospective Studies
Arteries
Lymph Nodes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Comparison of standard and Quadruple-Phase contrast Material injection for artifacts, image Quality, and radiation Dose in the evaluation of head and neck cancer Metastases. / Saade, Charbel; El-Merhi, Fadi; Mayat, Ahmad; Brennan, Patrick C.; Yousem, David Mark.

In: Radiology, Vol. 279, No. 2, 01.05.2016, p. 571-577.

Research output: Contribution to journalArticle

@article{c88c8babd0ef4c2586814e3cb157db59,
title = "Comparison of standard and Quadruple-Phase contrast Material injection for artifacts, image Quality, and radiation Dose in the evaluation of head and neck cancer Metastases",
abstract = "Purpose: To investigate opacification of head and neck vasculature during computed tomography (CT) of supraclavicular lymph nodes with a quadruple-phase contrast media and saline dual-injection protocol. Materials and Methods: This retrospective study was institutional review board approved. In 180 consecutive patients, routine head and neck CT was performed with one of two protocols: protocol A, craniocaudal scan direction with 100 mL of contrast material injected intravenously as a single bolus; or protocol B, 100 mL of contrast material injected in four phases (phases 1-2, 60 mL of contrast material and saline injected at 2.5 mL/sec; phases 3-4, 40 mL of contrast material and saline injected at 2.5 mL/sec); both protocols had a fixed scan delay of 70 seconds. Attenuation of supraclavicular arteries and veins was measured with arteriovenous contrast ratio (AVCR) and contrast-to-noise ratio (CNR). Effective dose was calculated. Data were compared with the two-sample t test. Receiver operating characteristic (ROC) and visual grading characteristic analyses were performed. Results: Arterial attenuation was up to 20{\%} higher (P",
author = "Charbel Saade and Fadi El-Merhi and Ahmad Mayat and Brennan, {Patrick C.} and Yousem, {David Mark}",
year = "2016",
month = "5",
day = "1",
doi = "10.1148/radiol.2015150511",
language = "English (US)",
volume = "279",
pages = "571--577",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "2",

}

TY - JOUR

T1 - Comparison of standard and Quadruple-Phase contrast Material injection for artifacts, image Quality, and radiation Dose in the evaluation of head and neck cancer Metastases

AU - Saade, Charbel

AU - El-Merhi, Fadi

AU - Mayat, Ahmad

AU - Brennan, Patrick C.

AU - Yousem, David Mark

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Purpose: To investigate opacification of head and neck vasculature during computed tomography (CT) of supraclavicular lymph nodes with a quadruple-phase contrast media and saline dual-injection protocol. Materials and Methods: This retrospective study was institutional review board approved. In 180 consecutive patients, routine head and neck CT was performed with one of two protocols: protocol A, craniocaudal scan direction with 100 mL of contrast material injected intravenously as a single bolus; or protocol B, 100 mL of contrast material injected in four phases (phases 1-2, 60 mL of contrast material and saline injected at 2.5 mL/sec; phases 3-4, 40 mL of contrast material and saline injected at 2.5 mL/sec); both protocols had a fixed scan delay of 70 seconds. Attenuation of supraclavicular arteries and veins was measured with arteriovenous contrast ratio (AVCR) and contrast-to-noise ratio (CNR). Effective dose was calculated. Data were compared with the two-sample t test. Receiver operating characteristic (ROC) and visual grading characteristic analyses were performed. Results: Arterial attenuation was up to 20% higher (P

AB - Purpose: To investigate opacification of head and neck vasculature during computed tomography (CT) of supraclavicular lymph nodes with a quadruple-phase contrast media and saline dual-injection protocol. Materials and Methods: This retrospective study was institutional review board approved. In 180 consecutive patients, routine head and neck CT was performed with one of two protocols: protocol A, craniocaudal scan direction with 100 mL of contrast material injected intravenously as a single bolus; or protocol B, 100 mL of contrast material injected in four phases (phases 1-2, 60 mL of contrast material and saline injected at 2.5 mL/sec; phases 3-4, 40 mL of contrast material and saline injected at 2.5 mL/sec); both protocols had a fixed scan delay of 70 seconds. Attenuation of supraclavicular arteries and veins was measured with arteriovenous contrast ratio (AVCR) and contrast-to-noise ratio (CNR). Effective dose was calculated. Data were compared with the two-sample t test. Receiver operating characteristic (ROC) and visual grading characteristic analyses were performed. Results: Arterial attenuation was up to 20% higher (P

UR - http://www.scopus.com/inward/record.url?scp=84965136600&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84965136600&partnerID=8YFLogxK

U2 - 10.1148/radiol.2015150511

DO - 10.1148/radiol.2015150511

M3 - Article

C2 - 26624972

AN - SCOPUS:84965136600

VL - 279

SP - 571

EP - 577

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 2

ER -