Comparison of simple sugar/salt versus glucose/electrolyte oral rehydration solutions in infant diarrhoea

M. L. Clements, M. M. Levine, F. Cleaves, T. P. Hughes, M. Caceres, E. Aleman, R. E. Black, J. Rust

Research output: Contribution to journalArticle

Abstract

In a randomized double-blind trial, infants with mild or moderate diarrhoeal dehydration were rehydrated orally either with a simple solution containing table sugar and salt (without potassium or bicarbonate) or with a complete glucose/electrolyte solution and 27 (93%) of 29 infants given sugar/salt were successfully rehydrated with similar improvement in metabolic acidosis and rapidity of rehydration. The drawbacks to oral therapy with simple sugar/salt solution were the frequent development of hypokalaemia and greater volume of vomiting during treatment. Carefully prepared sugar/salt solution, if accompanied by adequate potassium supplementation, may be used as an alternative to the preferred glucose/electrolyte formula when the latter is unavailable.

Original languageEnglish (US)
Pages (from-to)189-194
Number of pages6
JournalJournal of Tropical Medicine and Hygiene
Volume84
Issue number5
StatePublished - Dec 1 1981
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Environmental Science(all)
  • Engineering(all)
  • Infectious Diseases
  • Earth and Planetary Sciences(all)

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  • Cite this

    Clements, M. L., Levine, M. M., Cleaves, F., Hughes, T. P., Caceres, M., Aleman, E., Black, R. E., & Rust, J. (1981). Comparison of simple sugar/salt versus glucose/electrolyte oral rehydration solutions in infant diarrhoea. Journal of Tropical Medicine and Hygiene, 84(5), 189-194.