Comparison of oxygenation measurements in pediatric patients during sickle cell crises

J. A. Craft, E. Alessandrini, L. B. Kenney, B. Klein, G. Bray, N. L.C. Luban, R. Meek, V. M. Nadkarni

Research output: Contribution to journalArticlepeer-review

Abstract

Measurements of the saturation of arterial blood with oxygen (Sao2) were compared in 24 children during sickle cell crises. Simultaneous pulse oximetry (Nellcor N-100 pulse oximeter) and arterial blood analysis showed that Sao2 measured by pulse oximetry overestimated cooximeter-measured Sao2 (mean bias, 6.9%; p < 0.001). The blood gas machine–calculated Sao2 also overestimated cooximeter-measured Sao2 (p < 0.001). The bias increased with increasing age (p = 0.002) and carboxyhemoglobin level (p = 0.005) but was not related to methemoglobin, total hemoglobin, percentage of hemoglobin S, or percentage of hemoglobin F. (J PEDIATR 1994;124:93-5)

Original languageEnglish (US)
Pages (from-to)93-95
Number of pages3
JournalJournal of Pediatrics
Volume124
Issue number1
DOIs
StatePublished - 1994
Externally publishedYes

Keywords

  • CI
  • COHb
  • Carboxyhemoglobin
  • Confidence interval
  • Fetal hemoglobin
  • HbF
  • HbS
  • MetHb
  • Methemoglobin
  • SaO
  • Saturation of arterial blood with oxygen
  • Saturation of arterial blood with oxygen, measured by pulse oximetry
  • Sickle hemoglobin
  • SpO

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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