Comparison of orally administered metaproterenol and theophylline in the control of chronic asthma

Paul S. Lietman, Lois Dusdieker, Michael Green, Gary D. Smith, Edem E. Ekwo, Miles Weinberger

Research output: Contribution to journalArticle

Abstract

The efficacy of metaproterenol (orciprénaline) and theophylline given orally at currently recommended doses was examined in 34 children with chronic asthma using a randomized double-blind cross-over evaluation of four weeks' duration for each active regimen. No serious adverse effects were seen with either medication, but tremor occurred more frequently with metaproterenol (P0.05). Symptoms of wheezing, coughing, exercise intolerance, and interference with sleep were more frequently associated with the oral metaproterenol regimen; completely asymptomatic days occurred 50% more frequently in association with theophylline therapy (P

Original languageEnglish (US)
Pages (from-to)281-287
Number of pages7
JournalJournal of Pediatrics
Volume101
Issue number2
DOIs
StatePublished - 1982
Externally publishedYes

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Metaproterenol
Theophylline
Asthma
Respiratory Sounds
Tremor
Sleep
Exercise
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Lietman, P. S., Dusdieker, L., Green, M., Smith, G. D., Ekwo, E. E., & Weinberger, M. (1982). Comparison of orally administered metaproterenol and theophylline in the control of chronic asthma. Journal of Pediatrics, 101(2), 281-287. https://doi.org/10.1016/S0022-3476(82)80142-X

Comparison of orally administered metaproterenol and theophylline in the control of chronic asthma. / Lietman, Paul S.; Dusdieker, Lois; Green, Michael; Smith, Gary D.; Ekwo, Edem E.; Weinberger, Miles.

In: Journal of Pediatrics, Vol. 101, No. 2, 1982, p. 281-287.

Research output: Contribution to journalArticle

Lietman, PS, Dusdieker, L, Green, M, Smith, GD, Ekwo, EE & Weinberger, M 1982, 'Comparison of orally administered metaproterenol and theophylline in the control of chronic asthma', Journal of Pediatrics, vol. 101, no. 2, pp. 281-287. https://doi.org/10.1016/S0022-3476(82)80142-X
Lietman, Paul S. ; Dusdieker, Lois ; Green, Michael ; Smith, Gary D. ; Ekwo, Edem E. ; Weinberger, Miles. / Comparison of orally administered metaproterenol and theophylline in the control of chronic asthma. In: Journal of Pediatrics. 1982 ; Vol. 101, No. 2. pp. 281-287.
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