Abstract
Purpose: To compare MRI features of pathologically-proven hepatocellular carcinoma (HCC) between patients with hepatitis B (HBV) and hepatitis C (HCV) infection. Methods: Two radiologists assessed 51 confirmed HCCs on MRI in HBV (n. =. 18) or HCV (n. =. 33) patients; a third, more experienced, radiologist resolved discrepancies. Results: Arterial hyperenhancement occurred more frequently in HCV (90.9% vs. 66.7%; P. =. .032), DWI/T2WI hyperintensity more frequently in HBV [(DWI: 78.6% vs. 45.8%, T2WI: 77.8% vs. 48.5%; P = .073-0.088)]. Tumors were larger in HBV (P. ≤. .016). Washout, pseudocapsule, homogeneity, circumscribed margins, lipid, iron, and visually low ADC were not different. Conclusion: Larger studies are required to confirm these preliminary findings.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 352-356 |
| Number of pages | 5 |
| Journal | Clinical Imaging |
| Volume | 40 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1 2016 |
| Externally published | Yes |
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Keywords
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- MRI
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Comparison of MRI features of pathologically proven hepatocellular carcinoma between patients with hepatitis B and hepatitis C infection. / Dunst, Diane; Ream, Justin M.; Khalef, Victoria; Hajdu, Cristina H.; Rosenkrantz, Andrew B.
In: Clinical Imaging, Vol. 40, No. 3, 01.05.2016, p. 352-356.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of MRI features of pathologically proven hepatocellular carcinoma between patients with hepatitis B and hepatitis C infection
AU - Dunst, Diane
AU - Ream, Justin M.
AU - Khalef, Victoria
AU - Hajdu, Cristina H.
AU - Rosenkrantz, Andrew B.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Purpose: To compare MRI features of pathologically-proven hepatocellular carcinoma (HCC) between patients with hepatitis B (HBV) and hepatitis C (HCV) infection. Methods: Two radiologists assessed 51 confirmed HCCs on MRI in HBV (n. =. 18) or HCV (n. =. 33) patients; a third, more experienced, radiologist resolved discrepancies. Results: Arterial hyperenhancement occurred more frequently in HCV (90.9% vs. 66.7%; P. =. .032), DWI/T2WI hyperintensity more frequently in HBV [(DWI: 78.6% vs. 45.8%, T2WI: 77.8% vs. 48.5%; P = .073-0.088)]. Tumors were larger in HBV (P. ≤. .016). Washout, pseudocapsule, homogeneity, circumscribed margins, lipid, iron, and visually low ADC were not different. Conclusion: Larger studies are required to confirm these preliminary findings.
AB - Purpose: To compare MRI features of pathologically-proven hepatocellular carcinoma (HCC) between patients with hepatitis B (HBV) and hepatitis C (HCV) infection. Methods: Two radiologists assessed 51 confirmed HCCs on MRI in HBV (n. =. 18) or HCV (n. =. 33) patients; a third, more experienced, radiologist resolved discrepancies. Results: Arterial hyperenhancement occurred more frequently in HCV (90.9% vs. 66.7%; P. =. .032), DWI/T2WI hyperintensity more frequently in HBV [(DWI: 78.6% vs. 45.8%, T2WI: 77.8% vs. 48.5%; P = .073-0.088)]. Tumors were larger in HBV (P. ≤. .016). Washout, pseudocapsule, homogeneity, circumscribed margins, lipid, iron, and visually low ADC were not different. Conclusion: Larger studies are required to confirm these preliminary findings.
KW - Hepatitis B
KW - Hepatitis C
KW - Hepatocellular carcinoma
KW - MRI
UR - http://www.scopus.com/inward/record.url?scp=84959366446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959366446&partnerID=8YFLogxK
U2 - 10.1016/j.clinimag.2016.01.014
DO - 10.1016/j.clinimag.2016.01.014
M3 - Article
C2 - 27133666
AN - SCOPUS:84959366446
VL - 40
SP - 352
EP - 356
JO - Clinical Imaging
JF - Clinical Imaging
SN - 0899-7071
IS - 3
ER -