Comparison of methods to measure heart size using noncontrast-enhanced computed tomography: Correlation with left ventricular mass

Kurt R. Daniel, Alain G. Bertoni, Jingzhong Ding, Sara Johnston, Matthew J. Budoff, David A. Bluemke, J. Jeffrey Carr

Research output: Contribution to journalArticle

Abstract

OBJECTIVE:: Left ventricular (LV) mass is a useful independent predictor of cardiovascular events. We sought to develop a new correlate of LV mass using noncontrast-enhanced cardiac computed tomography (NCE-CCT). METHODS:: We assessed 22 different ventricular measurements made with NCE-CCT in 60 participants in the Multi-Ethnic Study of Atherosclerosis. The primary outcome was the correlation between the NCE-CCT measurements and magnetic resonance imaging (MRI)-derived LV mass. RESULTS:: Correlation coefficients (r) for the 22 NCE-CCT techniques in comparison to MRI-derived LV mass ranged from 0.12 to 0.80, with 14 of the 22 techniques having r > 0.7. The highest correlation was achieved using the modified Simpson Rule method to determine the biventricular volume (r ≤ 0.80; P < 0.001). Interrater reliability was good, with intraclass correlation coefficients of 0.84 to 0.90 for the best (r > 0.75) NCE-CCT methods. CONCLUSIONS:: Noncontrast-enhanced cardiac computed tomography measurements of both biventricular volume and LV volume correlated well with MRI-derived LV mass in a population free of clinical cardiovascular disease.

Original languageEnglish (US)
Pages (from-to)934-941
Number of pages8
JournalJournal of computer assisted tomography
Volume32
Issue number6
DOIs
StatePublished - Nov 1 2008

Keywords

  • Computed tomography
  • Hypertension
  • Left ventricular hypertrophy
  • Methods

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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