Comparison of lipids in total brain tissue from five mouse genotypes

J. Sampugna, Janice Clements, T. P. Carter, A. T. Campagnoni

Research output: Contribution to journalArticle

Abstract

Brain tissue from adult male and female mice of the C57BL/6J, C57BL/6J‐Aw—J, BALB/cJ, SJL/J, and DBA/2J genotypes was examined for brain weight, total protein, total lipid, cholesterol, phospholipid, plasmalogen, sulfatide, nonganglioside—glycolipid sphingosine, and ganglioside N‐acetyl neuraminic acid, fatty acid, and sphingosine. No significant differences were found between sexes for any of these constituents. When compared to the overall average obtained for other animals, the DBA/2J, C57BL/6J‐Aw−J, and BALB/cJ mice contained lower quantities of nonganglioside—glycolipid sphingosine. The DBA/2J and C57BL/6J‐Aw−J mice also contained lower quantities of plasmalogen and sulfatide compared to the overall averages obtained for the other genotypes. In addition, the sterol content in DBA/2J mice was significantly higher than the overall average value obtained for the other animals.

Original languageEnglish (US)
Pages (from-to)259-266
Number of pages8
JournalJournal of Neurobiology
Volume6
Issue number3
DOIs
StatePublished - May 1975

ASJC Scopus subject areas

  • Neuroscience(all)
  • Cellular and Molecular Neuroscience

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