Comparison of inhospital outcomes of surgical aortic valve replacement in hospitals with and without availability of a transcatheter aortic valve implantation program (from a nationally representative database)

Vikas Singh, Apurva O. Badheka, Samir V. Patel, Nileshkumar J. Patel, Badal Thakkar, Nilay Patel, Shilpkumar Arora, Nish Patel, Achint Patel, Chirag Savani, Abhijit Ghatak, Sidakpal S. Panaich, Sunny Jhamnani, Abhishek Deshmukh, Ankit Chothani, Rajesh Sonani, Aashay Patel, Parth Bhatt, Abhishek Dave, Ronak BhimaniTamam Mohamad, Cindy Grines, Michael Cleman, John K. Forrest, Abeel Mangi

Research output: Contribution to journalArticlepeer-review

Abstract

We hypothesized that the availability of a transcatheter aortic valve implantation (TAVI) program in hospitals impacts the overall management of patients with aortic valve disease and hence may also improve postprocedural outcomes of conventional surgical aortic valve replacement (SAVR). The aim of the present study was to compare the inhospital outcomes of SAVR in centers with versus without availability of a TAVI program in an unrestricted large nationwide patient population >50 years of age. SAVRs performed on patients aged >50 years were identified from the Nationwide Inpatient Sample (NIS) for the years 2011 and 2012 using the International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes. SAVR cases were divided into 2 categories: those performed at hospitals with a TAVI program (SAVR-TAVI) and those without (SAVR-non-TAVI). A total of 9,674 SAVR procedures were identified: 4,526 (46.79%) in the SAVR-TAVI group and 5,148 (53.21%) in SAVR-non-TAVI group. The mean age of the study population was 70.2 ± 0.1 years with majority (53%) of the patients aged >70 years. The mean Charlson's co-morbidity score for patients in SAVR-TAVI group was greater (greater percentage of patients were aged >80 years, had hypertension, congestive heart failure, renal failure, and peripheral arterial disease) than that of patients in SAVR-non-TAVI group (1.6 vs 1.4, p <0.001). The propensity score matching analysis showed a statistically significant lower inhospital mortality (1.25% vs 1.72%, p = 0.001) and complications rate (35.6% vs 37.3%, p = 0.004) in SAVR-TAVI group compared to SAVR-non-TAVI group. The mean length of hospital stay was similar in the 2 groups the cost of hospitalization was higher in the SAVR-TAVI group ($43,894 ± 483 vs $41,032 ± 473, p <0.0001). Having a TAVI program was a significant predictor of reduced mortality and complications rate after SAVR in multivariate analysis. In conclusion, this largest direct comparative analysis demonstrates that SAVRs performed in centers with a TAVI program are associated with significantly lower mortality and complications rates compared to those performed in centers without a TAVI program.

Original languageEnglish (US)
Pages (from-to)1229-1236
Number of pages8
JournalAmerican Journal of Cardiology
Volume116
Issue number8
DOIs
StatePublished - Oct 15 2015
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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