Comparison of CT versus MRI measurements of transverse atlantal ligament integrity in craniovertebral junction injuries. Part 1: A clinical study

Luis Perez-Orribo, Laura A. Snyder, Samuel Kalb, Ali M. Elhadi, Forrest Hsu, Anna G.U.S. Newcomb, Devika Malhotra, Neil R. Crawford, Nicholas Theodore

Research output: Contribution to journalArticle

Abstract

OBJECTIVE Craniovertebral junction (CVJ) injuries complicated by transverse atlantal ligament (TAL) disruption often require surgical stabilization. Measurements based on the atlantodental interval (ADI), atlas lateral diameter (ALD1), and axis lateral diameter (ALD2) may help clinicians identify TAL disruption. This study used CT scanning to evaluate the reliability of these measurements and other variants in the clinical setting. METHODS Patients with CVJ injuries treated at the authors' institution between 2004 and 2011 were evaluated retrospectively for demographics, mechanism and location of CVJ injury, classification of injury, treatment, and modified Japanese Orthopaedic Association score at the time of injury and follow-up. The integrity of the TAL was evaluated using MRI. The ADI, ALD1, and ALD2 were measured on CT to identify TAL disruption indirectly. RESULTS Among the 125 patients identified, 40 (32%) had atlas fractures, 59 (47.2%) odontoid fractures, 31 (24.8%) axis fractures, and 4 (3.2%) occipital condyle fractures. TAL disruption was documented on MRI in 11 cases (8.8%). The average ADI for TAL injury was 1.8 mm (range 0.9-3.9 mm). Nine (81.8%) of the 11 patients with TAL injury had an ADI of less than 3 mm. In 10 patients (90.9%) with TAL injury, overhang of the C-1 lateral masses on C-2 was less than 7 mm. ADI, ALD1, ALD2, ALD1 - ALD2, and ALD1/ALD2 did not correlate with the integrity of the TAL. CONCLUSIONS No current measurement method using CT, including the ADI, ALD1, and ALD2 or their differences or ratios, consistently indicates the integrity of the TAL. A more reliable CT-based criterion is needed to diagnose TAL disruption when MRI is unavailable.

Original languageEnglish (US)
Pages (from-to)897-902
Number of pages6
JournalJournal of neurosurgery. Spine
Volume24
Issue number6
DOIs
StatePublished - Jun 1 2016
Externally publishedYes

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Ligaments
Wounds and Injuries
Atlases
Clinical Studies
Demography
Bone and Bones

Keywords

  • ADI = atlantodental interval
  • ALD1 = atlas lateral diameter
  • ALD2 = axis lateral diameter
  • atlantoaxial overhang
  • atlantodental interval
  • atlas fracture
  • axis fracture
  • cervical
  • CVJ = craniovertebral junction
  • GCS = Glasgow Coma Scale
  • measurement
  • mJOA = modified Japanese Orthopaedic Association
  • TAL = transverse atlantal ligament
  • transverse atlantal ligament

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Comparison of CT versus MRI measurements of transverse atlantal ligament integrity in craniovertebral junction injuries. Part 1 : A clinical study. / Perez-Orribo, Luis; Snyder, Laura A.; Kalb, Samuel; Elhadi, Ali M.; Hsu, Forrest; Newcomb, Anna G.U.S.; Malhotra, Devika; Crawford, Neil R.; Theodore, Nicholas.

In: Journal of neurosurgery. Spine, Vol. 24, No. 6, 01.06.2016, p. 897-902.

Research output: Contribution to journalArticle

Perez-Orribo, Luis ; Snyder, Laura A. ; Kalb, Samuel ; Elhadi, Ali M. ; Hsu, Forrest ; Newcomb, Anna G.U.S. ; Malhotra, Devika ; Crawford, Neil R. ; Theodore, Nicholas. / Comparison of CT versus MRI measurements of transverse atlantal ligament integrity in craniovertebral junction injuries. Part 1 : A clinical study. In: Journal of neurosurgery. Spine. 2016 ; Vol. 24, No. 6. pp. 897-902.
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abstract = "OBJECTIVE Craniovertebral junction (CVJ) injuries complicated by transverse atlantal ligament (TAL) disruption often require surgical stabilization. Measurements based on the atlantodental interval (ADI), atlas lateral diameter (ALD1), and axis lateral diameter (ALD2) may help clinicians identify TAL disruption. This study used CT scanning to evaluate the reliability of these measurements and other variants in the clinical setting. METHODS Patients with CVJ injuries treated at the authors' institution between 2004 and 2011 were evaluated retrospectively for demographics, mechanism and location of CVJ injury, classification of injury, treatment, and modified Japanese Orthopaedic Association score at the time of injury and follow-up. The integrity of the TAL was evaluated using MRI. The ADI, ALD1, and ALD2 were measured on CT to identify TAL disruption indirectly. RESULTS Among the 125 patients identified, 40 (32{\%}) had atlas fractures, 59 (47.2{\%}) odontoid fractures, 31 (24.8{\%}) axis fractures, and 4 (3.2{\%}) occipital condyle fractures. TAL disruption was documented on MRI in 11 cases (8.8{\%}). The average ADI for TAL injury was 1.8 mm (range 0.9-3.9 mm). Nine (81.8{\%}) of the 11 patients with TAL injury had an ADI of less than 3 mm. In 10 patients (90.9{\%}) with TAL injury, overhang of the C-1 lateral masses on C-2 was less than 7 mm. ADI, ALD1, ALD2, ALD1 - ALD2, and ALD1/ALD2 did not correlate with the integrity of the TAL. CONCLUSIONS No current measurement method using CT, including the ADI, ALD1, and ALD2 or their differences or ratios, consistently indicates the integrity of the TAL. A more reliable CT-based criterion is needed to diagnose TAL disruption when MRI is unavailable.",
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AU - Kalb, Samuel

AU - Elhadi, Ali M.

AU - Hsu, Forrest

AU - Newcomb, Anna G.U.S.

AU - Malhotra, Devika

AU - Crawford, Neil R.

AU - Theodore, Nicholas

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N2 - OBJECTIVE Craniovertebral junction (CVJ) injuries complicated by transverse atlantal ligament (TAL) disruption often require surgical stabilization. Measurements based on the atlantodental interval (ADI), atlas lateral diameter (ALD1), and axis lateral diameter (ALD2) may help clinicians identify TAL disruption. This study used CT scanning to evaluate the reliability of these measurements and other variants in the clinical setting. METHODS Patients with CVJ injuries treated at the authors' institution between 2004 and 2011 were evaluated retrospectively for demographics, mechanism and location of CVJ injury, classification of injury, treatment, and modified Japanese Orthopaedic Association score at the time of injury and follow-up. The integrity of the TAL was evaluated using MRI. The ADI, ALD1, and ALD2 were measured on CT to identify TAL disruption indirectly. RESULTS Among the 125 patients identified, 40 (32%) had atlas fractures, 59 (47.2%) odontoid fractures, 31 (24.8%) axis fractures, and 4 (3.2%) occipital condyle fractures. TAL disruption was documented on MRI in 11 cases (8.8%). The average ADI for TAL injury was 1.8 mm (range 0.9-3.9 mm). Nine (81.8%) of the 11 patients with TAL injury had an ADI of less than 3 mm. In 10 patients (90.9%) with TAL injury, overhang of the C-1 lateral masses on C-2 was less than 7 mm. ADI, ALD1, ALD2, ALD1 - ALD2, and ALD1/ALD2 did not correlate with the integrity of the TAL. CONCLUSIONS No current measurement method using CT, including the ADI, ALD1, and ALD2 or their differences or ratios, consistently indicates the integrity of the TAL. A more reliable CT-based criterion is needed to diagnose TAL disruption when MRI is unavailable.

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KW - GCS = Glasgow Coma Scale

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KW - mJOA = modified Japanese Orthopaedic Association

KW - TAL = transverse atlantal ligament

KW - transverse atlantal ligament

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