Comparison of computer simulated and phantom measured phase variance in the study of trabecular bone

Evangelia Mihalopoulou, Sophie Allein, Robert Luypaert, Henri Eisendrath, Anastasios Bezerianos, George Panayiotakis

Research output: Contribution to journalArticlepeer-review

Abstract

A new method using magnetic resonance phase images for the assessment of trabecular bone structure has recently been proposed. To test this method, a mathematical model is developed which calculates the phase distribution in gradient echo acquired phase images of a structure of Pyrex glass rods immersed in a copper sulfate solution. Several experiments were performed using a phantom built in the same way as the structure used in the mathematical model. The results from the model are compared with those from the phantom tests, and the influence of resolution and bone area fraction on the phase dispersion is studied. The good correlation between theoretical and experimental results shows that phase variance increases with increasing resolution and bone density. However, the dependence of variance on bone density is less prominent for large pixel sizes.

Original languageEnglish (US)
Pages (from-to)29-36
Number of pages8
JournalMagnetic Resonance Imaging
Volume16
Issue number1
DOIs
StatePublished - Jan 1998

Keywords

  • Magnetic resonance
  • Model
  • Phase imaging
  • Trabecular bone

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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