@article{22e40481817a46b1af993ea18373a6b6,
title = "Comparison of anthropometric indicators to predict mortality in a population-based prospective study of children under 5 years in Niger",
abstract = "Objective: In the present study, we aimed to compare anthropometric indicators as predictors of mortality in a community-based setting.Design: We conducted a population-based longitudinal study nested in a cluster-randomized trial. We assessed weight, height and mid-upper arm circumference (MUAC) on children 12 months after the trial began and used the trial's annual census and monitoring visits to assess mortality over 2 years.Setting: Niger.Participants: Children aged 6-60 months during the study.Results: Of 1023 children included in the study at baseline, height-for-age Z-score, weight-for-age Z-score, weight-for-height Z-score and MUAC classified 777 (76·0 %), 630 (61·6 %), 131 (12·9 %) and eighty (7·8 %) children as moderately to severely malnourished, respectively. Over the 2-year study period, fifty-eight children (5·7 %) died. MUAC had the greatest AUC (0·68, 95 % CI 0·61, 0·75) and had the strongest association with mortality in this sample (hazard ratio = 2·21, 95 % CI 1·26, 3·89, P = 0·006).Conclusions: MUAC appears to be a better predictor of mortality than other anthropometric indicators in this community-based, high-malnutrition setting in Niger.",
keywords = "Anthropometry, Malnutrition, Mortality, Niger",
author = "O'Brien, {Kieran S.} and Abdou Amza and Boubacar Kadri and Beido Nassirou and Cotter, {Sun Y.} and Stoller, {Nicole E.} and West, {Sheila K.} and Bailey, {Robin L.} and Porco, {Travis C.} and Keenan, {Jeremy D.} and Lietman, {Thomas M.} and Oldenburg, {Catherine E.}",
note = "Funding Information: Acknowledgements: The authors would like to thank the Data and Safety Monitoring Committee, including Douglas Jabs, MD, MBA (chair); Antoinette Darville, MD; Maureen Maguire, PhD; and Grace Saguti, MD, who were generous with their time and advice before and during the study. The authors thank Kurt Dreger, who designed and maintained the database, and the team in Niger at Programme National de Sant{\'e} Oculaire who helped implement the study. Financial support: This work was supported by the Bill and Melinda Gates Foundation (grant number 48027); the National Institutes of Health (grant numbers NIH/NEI K23 EYO19881-01 and NIH/NCRR/OD UCSF-CTSI KL2 RR024130); Research to Prevent Blindness; That Man May See; the Harper-Inglis Trust; and the Peierls Foundation. The funders had no role in the design, analysis or writing of this article. Conflict of interest: None. Authorship: K.S.O. formulated the research question, analysed the data and contributed to the writing of this article. A.A., B.K., B.N., S.Y.C., N.E.S., S.K.W., R.L.B., T.C.P., J.D.K. and T.M.L. designed and implemented the original trial and contributed to the writing of this article. C.E.O. formulated the research question and contributed to the writing of this article. Ethics of human subject participation: This study was conducted according to the guidelines laid down in the Declaration of Helsinki and all procedures involving human subjects were approved by the University of California San Francisco Committee for Human Research and the Comit{\'e} d{\textquoteright}Ethique du Niger (the Ethical Committee of Niger). Verbal informed consent was obtained from all subjects. Verbal consent was witnessed and formally recorded. Publisher Copyright: {\textcopyright} 2019 The Authors.",
year = "2020",
month = feb,
day = "1",
doi = "10.1017/S1368980019002520",
language = "English (US)",
volume = "23",
pages = "538--543",
journal = "Public health nutrition",
issn = "1368-9800",
publisher = "Cambridge University Press",
number = "3",
}