Comparison of a supplemented Rose questionnaire to exercise thallium testing in men and women

Eric B Bass, William P. Follansbee, Trevor J. Orchard

Research output: Contribution to journalArticle

Abstract

The Rose Questionnaire has had high specificity and variable sensitivity when compared to physician identification of the symptom complex of angina pectoris. We assessed the accuracy of a supplemented Rose Questionnaire in a series of 198 patients by comparing the Questionnaire to exercise thallium test evidence of coronary artery disease. The Rose diagnosis of angina had 26% sensitivity, 79% specificity, 42% positive predictive value, and 65% negative predictive value. The Rose diagnosis of myocardial infarction had 26% sensitivity and 90% specificity. The Rose diagnosis of angina or infarction yielded a sensitivity of 44%, specificity of 72%, positive predictive value of 67%, and negative predictive value of 50%. Supplemental questions designed to identify atypical ischemic pain led to increased sensitivity of up to 68% that was offset by decreased specificity. While the Questionnaire's sensitivity for coronary disease was greater for women than men (57 vs 40%), the overall accuracy was the same because specificity was lower (63 vs 80%).

Original languageEnglish (US)
Pages (from-to)385-394
Number of pages10
JournalJournal of Clinical Epidemiology
Volume42
Issue number5
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Thallium
Exercise
Sensitivity and Specificity
Angina Pectoris
Exercise Test
Infarction
Coronary Disease
Coronary Artery Disease
Myocardial Infarction
Physicians
Pain
Surveys and Questionnaires

Keywords

  • Coronary disease
  • Rose Questionnaire
  • Thallium

ASJC Scopus subject areas

  • Medicine(all)
  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Comparison of a supplemented Rose questionnaire to exercise thallium testing in men and women. / Bass, Eric B; Follansbee, William P.; Orchard, Trevor J.

In: Journal of Clinical Epidemiology, Vol. 42, No. 5, 1989, p. 385-394.

Research output: Contribution to journalArticle

Bass, Eric B ; Follansbee, William P. ; Orchard, Trevor J. / Comparison of a supplemented Rose questionnaire to exercise thallium testing in men and women. In: Journal of Clinical Epidemiology. 1989 ; Vol. 42, No. 5. pp. 385-394.
@article{84efb7be695843c6838cffaa07907973,
title = "Comparison of a supplemented Rose questionnaire to exercise thallium testing in men and women",
abstract = "The Rose Questionnaire has had high specificity and variable sensitivity when compared to physician identification of the symptom complex of angina pectoris. We assessed the accuracy of a supplemented Rose Questionnaire in a series of 198 patients by comparing the Questionnaire to exercise thallium test evidence of coronary artery disease. The Rose diagnosis of angina had 26{\%} sensitivity, 79{\%} specificity, 42{\%} positive predictive value, and 65{\%} negative predictive value. The Rose diagnosis of myocardial infarction had 26{\%} sensitivity and 90{\%} specificity. The Rose diagnosis of angina or infarction yielded a sensitivity of 44{\%}, specificity of 72{\%}, positive predictive value of 67{\%}, and negative predictive value of 50{\%}. Supplemental questions designed to identify atypical ischemic pain led to increased sensitivity of up to 68{\%} that was offset by decreased specificity. While the Questionnaire's sensitivity for coronary disease was greater for women than men (57 vs 40{\%}), the overall accuracy was the same because specificity was lower (63 vs 80{\%}).",
keywords = "Coronary disease, Rose Questionnaire, Thallium",
author = "Bass, {Eric B} and Follansbee, {William P.} and Orchard, {Trevor J.}",
year = "1989",
doi = "10.1016/0895-4356(89)90126-1",
language = "English (US)",
volume = "42",
pages = "385--394",
journal = "Journal of Clinical Epidemiology",
issn = "0895-4356",
publisher = "Elsevier USA",
number = "5",

}

TY - JOUR

T1 - Comparison of a supplemented Rose questionnaire to exercise thallium testing in men and women

AU - Bass, Eric B

AU - Follansbee, William P.

AU - Orchard, Trevor J.

PY - 1989

Y1 - 1989

N2 - The Rose Questionnaire has had high specificity and variable sensitivity when compared to physician identification of the symptom complex of angina pectoris. We assessed the accuracy of a supplemented Rose Questionnaire in a series of 198 patients by comparing the Questionnaire to exercise thallium test evidence of coronary artery disease. The Rose diagnosis of angina had 26% sensitivity, 79% specificity, 42% positive predictive value, and 65% negative predictive value. The Rose diagnosis of myocardial infarction had 26% sensitivity and 90% specificity. The Rose diagnosis of angina or infarction yielded a sensitivity of 44%, specificity of 72%, positive predictive value of 67%, and negative predictive value of 50%. Supplemental questions designed to identify atypical ischemic pain led to increased sensitivity of up to 68% that was offset by decreased specificity. While the Questionnaire's sensitivity for coronary disease was greater for women than men (57 vs 40%), the overall accuracy was the same because specificity was lower (63 vs 80%).

AB - The Rose Questionnaire has had high specificity and variable sensitivity when compared to physician identification of the symptom complex of angina pectoris. We assessed the accuracy of a supplemented Rose Questionnaire in a series of 198 patients by comparing the Questionnaire to exercise thallium test evidence of coronary artery disease. The Rose diagnosis of angina had 26% sensitivity, 79% specificity, 42% positive predictive value, and 65% negative predictive value. The Rose diagnosis of myocardial infarction had 26% sensitivity and 90% specificity. The Rose diagnosis of angina or infarction yielded a sensitivity of 44%, specificity of 72%, positive predictive value of 67%, and negative predictive value of 50%. Supplemental questions designed to identify atypical ischemic pain led to increased sensitivity of up to 68% that was offset by decreased specificity. While the Questionnaire's sensitivity for coronary disease was greater for women than men (57 vs 40%), the overall accuracy was the same because specificity was lower (63 vs 80%).

KW - Coronary disease

KW - Rose Questionnaire

KW - Thallium

UR - http://www.scopus.com/inward/record.url?scp=0024319474&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024319474&partnerID=8YFLogxK

U2 - 10.1016/0895-4356(89)90126-1

DO - 10.1016/0895-4356(89)90126-1

M3 - Article

C2 - 2732767

AN - SCOPUS:0024319474

VL - 42

SP - 385

EP - 394

JO - Journal of Clinical Epidemiology

JF - Journal of Clinical Epidemiology

SN - 0895-4356

IS - 5

ER -