The immune adherence technique was modified to permit a direct comparison between the reactivity of lymphocytes and kidney cells from the same person. These two cells were typed using 17 well characterized antisera. There were 82 significant discrepancies from a total of 234 direct comparisons. Absorptions with the negatively reacting cell resulted in diminished or absent serological activity against the positive cell type. The results support the concept that significant quantitative differences in the expression of isoantigens exist among different cell types.
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