Comparative study of two flat-panel X-Ray detectors applied to small-animal imaging cone-beam micro-CT

Alejandro Sisniega, Juan José Vaquero, Eduardo Lage, Álvaro De Carlos, José L. Villena, Mónica Abella, Irina Vidal, Gustavo Tapias, Jose Carlos Antoranz, Manuel Desco

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This work compares two different X-ray flat-panel detectors for its use in high-speed, cone-beam CT applied to small-animal imaging. The main differences between these two devices are the scintillators and the achievable frame rate. Both devices have been tested in terms of system linearity, sensitivity, resolution, stability and noise properties, taking into account the different timing schemes for each one of them and the mandatory corrections on the raw data. Tomographic scans have been carried out using both detectors to evaluate its final performance as well as the delivered dose needed to achieve similar quality scans. An experimental cone-beam CT test-bench has been designed and implemented to perform the different measurements. It uses a micro-focus X-ray source and a rotating stage where the samples are placed. A modified FDK algorithm has been used to reconstruct the acquired data. Both detectors show similar results for pixel linearity and stability measurements, and their noise levels are comparable. The resolution and sensitivity features are better for the direct grown scintillator detector (9 Ipmm vs. 6 Ipmm, and ∼4 times more sensitive for similar delivered dose). Since tomographic reconstructed images for the higher frame-rate detector show acceptable quality, it can be used to implement a faster system for high-speed acquisition techniques like, for example, dynamic imaging or gated protocols.

Original languageEnglish (US)
Title of host publication2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Pages3836-3840
Number of pages5
DOIs
StatePublished - Dec 1 2008
Externally publishedYes
Event2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 - Dresden, Germany
Duration: Oct 19 2008Oct 25 2008

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Other

Other2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
CountryGermany
CityDresden
Period10/19/0810/25/08

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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    Sisniega, A., Vaquero, J. J., Lage, E., Carlos, Á. D., Villena, J. L., Abella, M., Vidal, I., Tapias, G., Antoranz, J. C., & Desco, M. (2008). Comparative study of two flat-panel X-Ray detectors applied to small-animal imaging cone-beam micro-CT. In 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 (pp. 3836-3840). [4774118] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2008.4774118