Comparative effectiveness of acute therapies on lipoprotein cholesterol in hypothyroidism

G. S. Sundaram, Paul W Ladenson, S. Manimekalai

Research output: Contribution to journalArticle

Abstract

In conclusion, parenteral T3 50 mcg q.d. for one week is capable of normalizing serum and lipoprotein concentrations. T3 25 mcg q.d. and T4 100 mcg q.d., which produces a comparable serum T3 concentration by virtue of peripheral deiodination, have lesser effects on lipoprotein metabolism. These changes in circulating cholesterol concentrations are brought about by a decrease in the mass of circulating LDL and by alteration in the ratio of esterified to free cholesterol in serum, HDL2, and HDL3 with no associated changes in circulating bile acid concentrations.

Original languageEnglish (US)
Pages (from-to)501-505
Number of pages5
JournalAnnals of the New York Academy of Sciences
VolumeVOL. 435
StatePublished - 1984
Externally publishedYes

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Hypothyroidism
Lipoproteins
Cholesterol
Bile Acids and Salts
Serum
Metabolism
Therapeutics
lipoprotein cholesterol
Therapy
oxidized low density lipoprotein
Alteration

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Comparative effectiveness of acute therapies on lipoprotein cholesterol in hypothyroidism. / Sundaram, G. S.; Ladenson, Paul W; Manimekalai, S.

In: Annals of the New York Academy of Sciences, Vol. VOL. 435, 1984, p. 501-505.

Research output: Contribution to journalArticle

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