Abstract
We compared the efficacy of atorvastatin with pravastatin, simvastatin, fluvastatin, and lovastatin in 534 hypercholesterolemic patients in an 8- week, multicenter, randomized, open-label, parallel-group study. Atorvastatin 10, 20, and 40 mg produced significantly greater reductions (p ≤ .01) from baseline in low-density lipoprotein cholesterol and in total cholesterol than the milligram-equivalent doses of simvastatin, pravastatin, lovastatin, and fluvastatin. Safety profiles and tolerability wer similar for all the statins in this study.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 25-29 |
| Number of pages | 5 |
| Journal | Cardiology Review |
| Volume | 15 |
| Issue number | 12 |
| State | Published - Jan 1 1998 |
| Externally published | Yes |
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
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Cite this
Jones, P. H., & Blumenthal, R. S. (1998). Comparative dose efficacy of statins. Cardiology Review, 15(12), 25-29.