Comparative long-term performance characteristics of Bjork-Shiley mechanical and bioprosthetic valves were analyzed for patients undergoing aortic valve replacement between 1976 and 1981. A total of 419 patients received either a standard Bjork-Shiley (n = 266) or bioprosthetic (porcine, n = 126, or pericardial, n = 27) aortic valve. Cumulative patient follow-up was 1,705 patient-years; the average patient follow-up was 4.1 ± 2.7 years. Survival data were obtained for all but 11 patients (97% complete follow-up) up to 9 years after operation. Survival at 5 years was 81% ± 4% (± standard error) for Bjork-Shiley and for bioprosthetic valve recipients. Valve failure in the Bjork-Shiley group was predominately due to valve-related mortality and did not result from structural failure. Patients with bioprosthetic valves experienced valve failure as a result of prosthetic valve endocarditis and intrinsic valve degeneration. Although patients with bioprostheses experienced a lower incidence of valve-related morbidity than Bjork-Shiley valve recipients (p < 0.03), no difference could be demonstrated in the incidence of valve-related mortality or valve failure at 5 years between bioprosthetic and Bjork-Shiley valves. Mortality rate from valve failure was higher for Bjork-Shiley (86%, 12/14) than bioprosthetic valves (36%, 5/14) (p < 0.01).
|Original language||English (US)|
|Number of pages||14|
|Journal||Journal of Thoracic and Cardiovascular Surgery|
|State||Published - 1987|
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine