Comparative Analysis of Computed Tomographic and Magnetic Resonance Imaging Scans in Alzheimer Patients and Controls

Tamas Sandor, Ferenc Jolesz, James Tieman, Ron Kikinis, Kenneth Jones, Marilyn Albert

Research output: Contribution to journalArticlepeer-review

Abstract

Ten patients with Alzheimer's disease underwent computed tomography and magnetic resonance imaging at the same point in time. The mean Mini-Mental State examination score of the patients was 23, indicating that they were mildly impaired. Ten age-equivalent controls also obtained computed tomographic and magnetic resonance imaging scans. A semiautomated computer program analyzed nine comparable regions of interest on each set of scans. When regions of interest from both types of scans were combined in the same discriminant function analysis, the first two variables selected were from the magnetic resonance imaging data set, and they significantly differentiated 95% of the patients and controls.

Original languageEnglish (US)
Pages (from-to)381-384
Number of pages4
JournalArchives of neurology
Volume49
Issue number4
DOIs
StatePublished - Apr 1992
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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