Comorbidities and Chronic Obstructive Pulmonary Disease: Prevalence, Influence on Outcomes, and Management

Research output: Contribution to journalArticle

Abstract

Comorbidities impact a large proportion of patients with chronic obstructive pulmonary disease (COPD), with over 80% of patients with COPD estimated to have at least one comorbid chronic condition. Guidelines for the treatment of COPD are just now incorporating comorbidities to their management recommendations of COPD, and it is becoming increasingly clear that multimorbidity as well as specific comorbidities have strong associations with mortality and clinical outcomes in COPD, including dyspnea, exercise capacity, quality of life, healthcare utilization, and exacerbation risk. Appropriately, there has been an increased focus upon describing the burden of comorbidity in the COPD population and incorporating this information into existing efforts to better understand the clinical and phenotypic heterogeneity of this group. In this article, we summarize existing knowledge about comorbidity burden and specific comorbidities in COPD, focusing on prevalence estimates, association with outcomes, and existing knowledge about treatment strategies.

Original languageEnglish (US)
Pages (from-to)575-591
Number of pages17
JournalSeminars in Respiratory and Critical Care Medicine
Volume36
Issue number4
DOIs
StatePublished - Aug 5 2015

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Chronic Obstructive Pulmonary Disease
Comorbidity
Quality of Health Care
Dyspnea
Quality of Life
Guidelines
Exercise
Mortality
Therapeutics
Population

Keywords

  • clinical outcomes
  • comorbidity
  • COPD

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

Cite this

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