TY - JOUR
T1 - Comorbidities and Chronic Obstructive Pulmonary Disease
T2 - Prevalence, Influence on Outcomes, and Management
AU - Putcha, Nirupama
AU - Drummond, M. Bradley
AU - Wise, Robert A.
AU - Hansel, Nadia N.
PY - 2015/8/5
Y1 - 2015/8/5
N2 - Comorbidities impact a large proportion of patients with chronic obstructive pulmonary disease (COPD), with over 80% of patients with COPD estimated to have at least one comorbid chronic condition. Guidelines for the treatment of COPD are just now incorporating comorbidities to their management recommendations of COPD, and it is becoming increasingly clear that multimorbidity as well as specific comorbidities have strong associations with mortality and clinical outcomes in COPD, including dyspnea, exercise capacity, quality of life, healthcare utilization, and exacerbation risk. Appropriately, there has been an increased focus upon describing the burden of comorbidity in the COPD population and incorporating this information into existing efforts to better understand the clinical and phenotypic heterogeneity of this group. In this article, we summarize existing knowledge about comorbidity burden and specific comorbidities in COPD, focusing on prevalence estimates, association with outcomes, and existing knowledge about treatment strategies.
AB - Comorbidities impact a large proportion of patients with chronic obstructive pulmonary disease (COPD), with over 80% of patients with COPD estimated to have at least one comorbid chronic condition. Guidelines for the treatment of COPD are just now incorporating comorbidities to their management recommendations of COPD, and it is becoming increasingly clear that multimorbidity as well as specific comorbidities have strong associations with mortality and clinical outcomes in COPD, including dyspnea, exercise capacity, quality of life, healthcare utilization, and exacerbation risk. Appropriately, there has been an increased focus upon describing the burden of comorbidity in the COPD population and incorporating this information into existing efforts to better understand the clinical and phenotypic heterogeneity of this group. In this article, we summarize existing knowledge about comorbidity burden and specific comorbidities in COPD, focusing on prevalence estimates, association with outcomes, and existing knowledge about treatment strategies.
KW - COPD
KW - clinical outcomes
KW - comorbidity
UR - http://www.scopus.com/inward/record.url?scp=84938504757&partnerID=8YFLogxK
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U2 - 10.1055/s-0035-1556063
DO - 10.1055/s-0035-1556063
M3 - Article
C2 - 26238643
AN - SCOPUS:84938504757
SN - 1069-3424
VL - 36
SP - 575
EP - 591
JO - Seminars in Respiratory and Critical Care Medicine
JF - Seminars in Respiratory and Critical Care Medicine
IS - 4
ER -