Common variable immunodeficiency in a renal transplant patient with severe recurrent bacterial infection: A case report and review of the literature

Brent W. Miller, Daniel C. Brennan, Phillip E. Korenblat, John A. Goss, M. Wayne Flye

Research output: Contribution to journalArticlepeer-review

Abstract

The second reported case of common variable immunodeficiency (acquired agammaglobulinemia) after renal transplantation is presented. Agammaglobulinemia presumably resulted from long-standing immunosuppression. This case and our review of the literature indicate that agammaglobulinemia is a rare event after transplantation but can be treated successfully with intravenous immunoglobulin. Additionally, hypogammaglobulinemia occurs frequently after transplantation and should be monitored and treated in appropriate clinical situations. The treatment of our patient with intravenous immunoglobulin also suggests that patients with common variable immunodeficiency can undergo renal transplantation.

Original languageEnglish (US)
Pages (from-to)947-951
Number of pages5
JournalAmerican Journal of Kidney Diseases
Volume25
Issue number6
DOIs
StatePublished - Jun 1995
Externally publishedYes

Keywords

  • Agammaglobulinemia
  • renal transplantation

ASJC Scopus subject areas

  • Nephrology

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