Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

Jianfeng Xu, S. Lilly Zheng, Akira Komiya, Josyf C. Mychaleckyj, Sarah D. Isaacs, Baoli Chang, Aubrey R. Turner, Charles M. Ewing, Kathleen E. Wiley, Gregory A. Hawkins, Eugene R. Bleecker, Patrick Walsh, Deborah A. Meyers, William B Isaacs

Research output: Contribution to journalArticle

Abstract

Rare germline mutations of macrophage scavenger receptor 1 (MSR1) gene were reported to be associated with prostate cancer risk in families with hereditary prostate cancer (HPC) and in patients with non-HPC (Xu et al. 2002). To further evaluate the role of MSR1 in prostate cancer susceptibility, at Johns Hopkins Hospital, we studied five common variants of MSR1 in 301 patients with non-HPC who underwent prostate cancer treatment and in 250 control subjects who participated in prostate cancer-screening programs and had normal digital rectal examination and PSA levels (

Original languageEnglish (US)
Pages (from-to)208-212
Number of pages5
JournalAmerican Journal of Human Genetics
Volume72
Issue number1
DOIs
StatePublished - Jan 1 2003

Fingerprint

Scavenger Receptors
Prostatic Neoplasms
Genes
Digital Rectal Examination
Germ-Line Mutation
Early Detection of Cancer

ASJC Scopus subject areas

  • Genetics

Cite this

Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. / Xu, Jianfeng; Lilly Zheng, S.; Komiya, Akira; Mychaleckyj, Josyf C.; Isaacs, Sarah D.; Chang, Baoli; Turner, Aubrey R.; Ewing, Charles M.; Wiley, Kathleen E.; Hawkins, Gregory A.; Bleecker, Eugene R.; Walsh, Patrick; Meyers, Deborah A.; Isaacs, William B.

In: American Journal of Human Genetics, Vol. 72, No. 1, 01.01.2003, p. 208-212.

Research output: Contribution to journalArticle

Xu, J, Lilly Zheng, S, Komiya, A, Mychaleckyj, JC, Isaacs, SD, Chang, B, Turner, AR, Ewing, CM, Wiley, KE, Hawkins, GA, Bleecker, ER, Walsh, P, Meyers, DA & Isaacs, WB 2003, 'Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk', American Journal of Human Genetics, vol. 72, no. 1, pp. 208-212. https://doi.org/10.1086/345802
Xu, Jianfeng ; Lilly Zheng, S. ; Komiya, Akira ; Mychaleckyj, Josyf C. ; Isaacs, Sarah D. ; Chang, Baoli ; Turner, Aubrey R. ; Ewing, Charles M. ; Wiley, Kathleen E. ; Hawkins, Gregory A. ; Bleecker, Eugene R. ; Walsh, Patrick ; Meyers, Deborah A. ; Isaacs, William B. / Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. In: American Journal of Human Genetics. 2003 ; Vol. 72, No. 1. pp. 208-212.
@article{1d8faa4b2f994ba7be7056ca57acaf2e,
title = "Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk",
abstract = "Rare germline mutations of macrophage scavenger receptor 1 (MSR1) gene were reported to be associated with prostate cancer risk in families with hereditary prostate cancer (HPC) and in patients with non-HPC (Xu et al. 2002). To further evaluate the role of MSR1 in prostate cancer susceptibility, at Johns Hopkins Hospital, we studied five common variants of MSR1 in 301 patients with non-HPC who underwent prostate cancer treatment and in 250 control subjects who participated in prostate cancer-screening programs and had normal digital rectal examination and PSA levels (",
author = "Jianfeng Xu and {Lilly Zheng}, S. and Akira Komiya and Mychaleckyj, {Josyf C.} and Isaacs, {Sarah D.} and Baoli Chang and Turner, {Aubrey R.} and Ewing, {Charles M.} and Wiley, {Kathleen E.} and Hawkins, {Gregory A.} and Bleecker, {Eugene R.} and Patrick Walsh and Meyers, {Deborah A.} and Isaacs, {William B}",
year = "2003",
month = "1",
day = "1",
doi = "10.1086/345802",
language = "English (US)",
volume = "72",
pages = "208--212",
journal = "American Journal of Human Genetics",
issn = "0002-9297",
publisher = "Cell Press",
number = "1",

}

TY - JOUR

T1 - Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

AU - Xu, Jianfeng

AU - Lilly Zheng, S.

AU - Komiya, Akira

AU - Mychaleckyj, Josyf C.

AU - Isaacs, Sarah D.

AU - Chang, Baoli

AU - Turner, Aubrey R.

AU - Ewing, Charles M.

AU - Wiley, Kathleen E.

AU - Hawkins, Gregory A.

AU - Bleecker, Eugene R.

AU - Walsh, Patrick

AU - Meyers, Deborah A.

AU - Isaacs, William B

PY - 2003/1/1

Y1 - 2003/1/1

N2 - Rare germline mutations of macrophage scavenger receptor 1 (MSR1) gene were reported to be associated with prostate cancer risk in families with hereditary prostate cancer (HPC) and in patients with non-HPC (Xu et al. 2002). To further evaluate the role of MSR1 in prostate cancer susceptibility, at Johns Hopkins Hospital, we studied five common variants of MSR1 in 301 patients with non-HPC who underwent prostate cancer treatment and in 250 control subjects who participated in prostate cancer-screening programs and had normal digital rectal examination and PSA levels (

AB - Rare germline mutations of macrophage scavenger receptor 1 (MSR1) gene were reported to be associated with prostate cancer risk in families with hereditary prostate cancer (HPC) and in patients with non-HPC (Xu et al. 2002). To further evaluate the role of MSR1 in prostate cancer susceptibility, at Johns Hopkins Hospital, we studied five common variants of MSR1 in 301 patients with non-HPC who underwent prostate cancer treatment and in 250 control subjects who participated in prostate cancer-screening programs and had normal digital rectal examination and PSA levels (

UR - http://www.scopus.com/inward/record.url?scp=0037219568&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037219568&partnerID=8YFLogxK

U2 - 10.1086/345802

DO - 10.1086/345802

M3 - Article

VL - 72

SP - 208

EP - 212

JO - American Journal of Human Genetics

JF - American Journal of Human Genetics

SN - 0002-9297

IS - 1

ER -