Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families

William J. Rodriguez; Hyun Wha Kim; Carl D. Brandt; Robert H. Yolkcn; Maryann Richard; Julita O. Arrobio; Richard H. Schwartz; Albert Z. Kapikian; Robert M. Chanock; Robert H. Parrott

doi:10.1093/infdis/140.3.353

Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families

William J. Rodriguez, Hyun Wha Kim, Carl D. Brandt, Robert H. Yolkcn, Maryann Richard, Julita O. Arrobio, Richard H. Schwartz, Albert Z. Kapikian, Robert M. Chanock, Robert H. Parrott

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45 Scopus citations

Abstract

A sharp outbreak of gastroenteritis associated with human rotavirus type 2 involved not only all of nine infants and young children in a playgroup but also seven of 10 parents and grandparents studied. The source of the outbreak appeared to be two non-playgroup siblings. Six of 11 individuals studied shed human rotavirus type 2, and each of seven from whom paired sera were obtained developed a type 2 sero-response. Overall, evidence of infection with rotavirus type 2 was demonstrated in 10 of 11 individuals by detection of virus in stools and/or a serologic response in an enzyme-linked immunosorbent assay.

Original language	English (US)
Pages (from-to)	353-357
Number of pages	5
Journal	Journal of Infectious Diseases
Volume	140
Issue number	3
DOIs	https://doi.org/10.1093/infdis/140.3.353
State	Published - Sep 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Infectious Diseases

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10.1093/infdis/140.3.353

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Rodriguez, W. J., Kim, H. W., Brandt, C. D., Yolkcn, R. H., Richard, M., Arrobio, J. O., Schwartz, R. H., Kapikian, A. Z., Chanock, R. M., & Parrott, R. H. (1979). Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families. Journal of Infectious Diseases, 140(3), 353-357. https://doi.org/10.1093/infdis/140.3.353

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title = "Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families",

abstract = "A sharp outbreak of gastroenteritis associated with human rotavirus type 2 involved not only all of nine infants and young children in a playgroup but also seven of 10 parents and grandparents studied. The source of the outbreak appeared to be two non-playgroup siblings. Six of 11 individuals studied shed human rotavirus type 2, and each of seven from whom paired sera were obtained developed a type 2 sero-response. Overall, evidence of infection with rotavirus type 2 was demonstrated in 10 of 11 individuals by detection of virus in stools and/or a serologic response in an enzyme-linked immunosorbent assay.",

author = "Rodriguez, {William J.} and Kim, {Hyun Wha} and Brandt, {Carl D.} and Yolkcn, {Robert H.} and Maryann Richard and Arrobio, {Julita O.} and Schwartz, {Richard H.} and Kapikian, {Albert Z.} and Chanock, {Robert M.} and Parrott, {Robert H.}",

note = "Funding Information: This work was supported in part by contract no. I-AI 72535from the National Institute of Allergy and Infectious Diseases, National Institutes of Health.",

year = "1979",

month = sep,

doi = "10.1093/infdis/140.3.353",

language = "English (US)",

volume = "140",

pages = "353--357",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

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T1 - Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families

AU - Rodriguez, William J.

AU - Kim, Hyun Wha

AU - Brandt, Carl D.

AU - Yolkcn, Robert H.

AU - Richard, Maryann

AU - Arrobio, Julita O.

AU - Schwartz, Richard H.

AU - Kapikian, Albert Z.

AU - Chanock, Robert M.

AU - Parrott, Robert H.

N1 - Funding Information: This work was supported in part by contract no. I-AI 72535from the National Institute of Allergy and Infectious Diseases, National Institutes of Health.

PY - 1979/9

Y1 - 1979/9

N2 - A sharp outbreak of gastroenteritis associated with human rotavirus type 2 involved not only all of nine infants and young children in a playgroup but also seven of 10 parents and grandparents studied. The source of the outbreak appeared to be two non-playgroup siblings. Six of 11 individuals studied shed human rotavirus type 2, and each of seven from whom paired sera were obtained developed a type 2 sero-response. Overall, evidence of infection with rotavirus type 2 was demonstrated in 10 of 11 individuals by detection of virus in stools and/or a serologic response in an enzyme-linked immunosorbent assay.

AB - A sharp outbreak of gastroenteritis associated with human rotavirus type 2 involved not only all of nine infants and young children in a playgroup but also seven of 10 parents and grandparents studied. The source of the outbreak appeared to be two non-playgroup siblings. Six of 11 individuals studied shed human rotavirus type 2, and each of seven from whom paired sera were obtained developed a type 2 sero-response. Overall, evidence of infection with rotavirus type 2 was demonstrated in 10 of 11 individuals by detection of virus in stools and/or a serologic response in an enzyme-linked immunosorbent assay.

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Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families

Abstract

ASJC Scopus subject areas

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