Common Elements Treatment Approach (CETA) for unhealthy alcohol use among persons with HIV in Zambia: Study protocol of the ZCAP randomized controlled trial

Jeremy C. Kane, Anjali Sharma, Laura K. Murray, Geetanjali Chander, Tukiya Kanguya, Molly E. Lasater, Stephanie Skavenski, Ravi Paul, John Mayeya, Carla Kmett Danielson, Jenala Chipungu, Chipo Chitambi, Michael J. Vinikoor

Research output: Contribution to journalArticle

Abstract

Aims: Prevalence of unhealthy alcohol use and co-occurring mental health problems is high among persons living with HIV (PLWH) in sub-Saharan Africa (SSA). Yet, there is a dearth of evidence-based treatment options that can address both unhealthy alcohol use and comorbidities in SSA HIV care settings. Recent studies testing single-session alcohol brief interventions (BIs) among PLWH in SSA have suggested that more robust treatments are needed. This paper describes the protocol of a pilot randomized controlled superiority trial that will test the effectiveness of an evidence-based transdiagnostic multi-session psychotherapy, the Common Elements Treatment Approach (CETA), compared to a control condition consisting of a single session brief alcohol intervention (BI) based on CETA, at reducing unhealthy alcohol use, mental health problems, and other substance use among PLWH in urban Zambia. Methods: The study is a single-blind, parallel, individually randomized trial conducted in HIV treatment centers in Lusaka. 160 PLWH who meet criteria for unhealthy alcohol use + mental health or substance use comorbidities and/or have a more severe alcohol use disorder are eligible. Participants are randomized 1:1 to receive the single-session BI or CETA. Outcomes are assessed at baseline and a six-month follow-up and include unhealthy alcohol use, depression, trauma symptoms, and other substance use. Conclusions: The trial is a first step in establishing the effectiveness of CETA at reducing unhealthy alcohol use and comorbidities among PLWH in SSA. If effectiveness is demonstrated, a larger trial featuring long-term follow-ups and HIV treatment outcomes will be undertaken.

Original languageEnglish (US)
Article number100278
JournalAddictive Behaviors Reports
Volume12
DOIs
StatePublished - Dec 2020

Keywords

  • Brief intervention
  • HIV
  • Randomized controlled trial
  • Substance use
  • Transdiagnostic therapy
  • Unhealthy alcohol use
  • Zambia

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Common Elements Treatment Approach (CETA) for unhealthy alcohol use among persons with HIV in Zambia: Study protocol of the ZCAP randomized controlled trial'. Together they form a unique fingerprint.

  • Cite this

    Kane, J. C., Sharma, A., Murray, L. K., Chander, G., Kanguya, T., Lasater, M. E., Skavenski, S., Paul, R., Mayeya, J., Kmett Danielson, C., Chipungu, J., Chitambi, C., & Vinikoor, M. J. (2020). Common Elements Treatment Approach (CETA) for unhealthy alcohol use among persons with HIV in Zambia: Study protocol of the ZCAP randomized controlled trial. Addictive Behaviors Reports, 12, [100278]. https://doi.org/10.1016/j.abrep.2020.100278