Comment on “sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”

Abdel Aouacheria, Kyle W. Cunningham, J. Marie Hardwick, Zdena Palkova, Ted Powers, Fedor F. Severin, Libuše Váchova

Research output: Contribution to journalReview articlepeer-review

Abstract

Shlezinger et al. (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.

Original languageEnglish (US)
Article numbereaar6910
JournalScience
Volume360
Issue number6395
DOIs
StatePublished - Jun 22 2018

ASJC Scopus subject areas

  • General

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