TY - JOUR
T1 - Combined-Modality Therapy of Cancer
T2 - What is It and When Does It Work?
AU - Rosenberg, Steven A.
PY - 1985/6/6
Y1 - 1985/6/6
N2 - The three major methods of treatment for cancer are surgery, irradiation, and chemotherapy. Each has been shown to have considerable efficacy in the therapy of selected cancers, and each has its own advantages and toxic effects. It was realized early that the combined use of these approaches in a fashion carefully designed to optimize their advantages and interactions might produce better results than the use of any approach alone. Both practical and theoretical considerations made combined treatment attractive. When the complete surgical removal of a tumor involved loss of an extremity or of a nonvital organ, such as the rectum.
AB - The three major methods of treatment for cancer are surgery, irradiation, and chemotherapy. Each has been shown to have considerable efficacy in the therapy of selected cancers, and each has its own advantages and toxic effects. It was realized early that the combined use of these approaches in a fashion carefully designed to optimize their advantages and interactions might produce better results than the use of any approach alone. Both practical and theoretical considerations made combined treatment attractive. When the complete surgical removal of a tumor involved loss of an extremity or of a nonvital organ, such as the rectum.
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U2 - 10.1056/NEJM198506063122309
DO - 10.1056/NEJM198506063122309
M3 - Editorial
C2 - 3990752
AN - SCOPUS:0021823897
VL - 312
SP - 1512
EP - 1514
JO - New England Journal of Medicine
JF - New England Journal of Medicine
SN - 0028-4793
IS - 23
ER -