Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia

O. M. Wolkowitz, D. Pickar, A. R. Doran, A. Breier, J. Tarell, S. M. Paul

Research output: Contribution to journalArticle

Abstract

Alprazolam, when added under double-blind conditions to a stable neuroleptic regimen in two patients with schizophrenia, resulted in clinically apparent improvement in positive and negative schizophrenic symptoms. Both patients showed significant worsening of symptoms following reduction of discontinuation of alprazolam.

Original languageEnglish (US)
Pages (from-to)85-87
Number of pages3
JournalAmerican Journal of Psychiatry
Volume143
Issue number1
StatePublished - 1986
Externally publishedYes

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ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Wolkowitz, O. M., Pickar, D., Doran, A. R., Breier, A., Tarell, J., & Paul, S. M. (1986). Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia. American Journal of Psychiatry, 143(1), 85-87.