Collaborative networks for both improvement and research

Carolyn M. Clancy, Peter A. Margolis, Marlene Miller

Research output: Contribution to journalArticle

Abstract

Moving significant therapeutic discoveries beyond early biomedical translation or T1 science and into practice involves: (1) T2 science, identifying "the right treatment for the right patient in the right way at the right time" (eg, patient-centered outcomes research) and tools to implement this knowledge (eg, guidelines, registries); and (2) T3 studies addressing how to achieve health care delivery change. Collaborative improvement networks can serve as large-scale, health system laboratories to engage clinicians, researchers, patients, and parents in testing approaches to translate research into practice. Improvement networks are of particular importance for pediatric T2 and T3 research, as evidence to establish safety and efficacy of therapeutic interventions in children is often lacking. Networks for improvement and research are also consistent with the Institute of Medicine's Learning Healthcare Systems model in which learning networks provide a system for improving care and outcomes and generate new knowledge in near real-time. Creation of total population registries in collaborative network sites provides large, representative study samples with high-quality data that can be used to generate evidence and to inform clinical decision-making. Networks use collaboration, data, and quality-improvement methods to standardize practice. Therefore, variation in outcomes due to unreliable and unnecessary care delivery is reduced, increasing statistical power, and allowing a consistent baseline from which to test new strategies. In addition, collaborative networks for improvement and research offer the opportunity to not only make improvements but also to study improvements to determine which interventions and combination of strategies work best in what settings.

Original languageEnglish (US)
JournalPediatrics
Volume131
Issue numberSUPPL.4
DOIs
StatePublished - Jun 2013

Fingerprint

Research
Registries
Patient Outcome Assessment
Learning
Delivery of Health Care
National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
Patient Rights
Quality Improvement
Therapeutics
Parents
Research Personnel
Guidelines
Pediatrics
Safety
Health
Population
Data Accuracy
Clinical Decision-Making

Keywords

  • Learning healthcare system
  • Learning networks
  • Quality improvement
  • Rapid learning networks

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Arts and Humanities (miscellaneous)

Cite this

Clancy, C. M., Margolis, P. A., & Miller, M. (2013). Collaborative networks for both improvement and research. Pediatrics, 131(SUPPL.4). https://doi.org/10.1542/peds.2012-3786H

Collaborative networks for both improvement and research. / Clancy, Carolyn M.; Margolis, Peter A.; Miller, Marlene.

In: Pediatrics, Vol. 131, No. SUPPL.4, 06.2013.

Research output: Contribution to journalArticle

Clancy, CM, Margolis, PA & Miller, M 2013, 'Collaborative networks for both improvement and research', Pediatrics, vol. 131, no. SUPPL.4. https://doi.org/10.1542/peds.2012-3786H
Clancy, Carolyn M. ; Margolis, Peter A. ; Miller, Marlene. / Collaborative networks for both improvement and research. In: Pediatrics. 2013 ; Vol. 131, No. SUPPL.4.
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