Colcemid sensitivity of fission yeast and the isolation of colcemid-resistant mutants

Seymour Lederberg, Gail Stetten

Research output: Contribution to journalArticle

Abstract

Cell division of the fission yeast, Schizosaccharomyces pombe, is reversibly inhibited by the antimitotic agent Colcemid (N-deacetyl-N- methylcolchicine) in nutrient medium. Cell growth continues until all cells become nonseparating cell doublets in a V configuration. Mutants have been isolated capable of uninhibited growth in the presence of concentrations of Colcemid mycostatic for the parent strain.

Original languageEnglish (US)
Pages (from-to)485-487
Number of pages3
JournalScience
Volume168
Issue number3930
DOIs
StatePublished - Jan 1 1970

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Colcemid sensitivity of fission yeast and the isolation of colcemid-resistant mutants'. Together they form a unique fingerprint.

  • Cite this