Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study

Judith Saxton; Graham Ratcliff; Anne Newman; Steven Belle; Linda Fried; John Yee; Lewis Kuller

doi:10.1159/000026270

Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study

Judith Saxton, Graham Ratcliff, Anne Newman, Steven Belle, Linda Fried, John Yee, Lewis Kuller

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

The purpose of the present study was to investigate the relationship between performance on a comprehensive battery of neuropsychological tests and the presence of clinical, subclinical or no cardiovascular disease in an elderly community-dwelling population. The results confirm previous reports of significant associations of age, education and gender with test performance. When performance was examined controlling for these variables, significant associations of disease group were seen with five measures emphasizing speed of performance; Parts A and B of the Trail Making Test, the WAIS-R Digit Symbol and Block Design subtests and category verbal fluency. These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels. Copyright (C) 2000 S. Karger AG, Basel.

Original language	English (US)
Pages (from-to)	312-319
Number of pages	8
Journal	Neuroepidemiology
Volume	19
Issue number	6
DOIs	https://doi.org/10.1159/000026270
State	Published - 2000
Externally published	Yes

Keywords

Aging
Cardiovascular disease
Cognitive functioning

ASJC Scopus subject areas

Epidemiology
Clinical Neurology

Access to Document

10.1159/000026270

Cite this

@article{7fc0164747e24328a050fbd7c4372546,

title = "Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study",

abstract = "The purpose of the present study was to investigate the relationship between performance on a comprehensive battery of neuropsychological tests and the presence of clinical, subclinical or no cardiovascular disease in an elderly community-dwelling population. The results confirm previous reports of significant associations of age, education and gender with test performance. When performance was examined controlling for these variables, significant associations of disease group were seen with five measures emphasizing speed of performance; Parts A and B of the Trail Making Test, the WAIS-R Digit Symbol and Block Design subtests and category verbal fluency. These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels. Copyright (C) 2000 S. Karger AG, Basel.",

keywords = "Aging, Cardiovascular disease, Cognitive functioning",

author = "Judith Saxton and Graham Ratcliff and Anne Newman and Steven Belle and Linda Fried and John Yee and Lewis Kuller",

year = "2000",

doi = "10.1159/000026270",

language = "English (US)",

volume = "19",

pages = "312--319",

journal = "Neuroepidemiology",

issn = "0251-5350",

publisher = "S. Karger AG",

number = "6",

}

TY - JOUR

T1 - Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study

AU - Saxton, Judith

AU - Ratcliff, Graham

AU - Newman, Anne

AU - Belle, Steven

AU - Fried, Linda

AU - Yee, John

AU - Kuller, Lewis

PY - 2000

Y1 - 2000

N2 - The purpose of the present study was to investigate the relationship between performance on a comprehensive battery of neuropsychological tests and the presence of clinical, subclinical or no cardiovascular disease in an elderly community-dwelling population. The results confirm previous reports of significant associations of age, education and gender with test performance. When performance was examined controlling for these variables, significant associations of disease group were seen with five measures emphasizing speed of performance; Parts A and B of the Trail Making Test, the WAIS-R Digit Symbol and Block Design subtests and category verbal fluency. These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels. Copyright (C) 2000 S. Karger AG, Basel.

AB - The purpose of the present study was to investigate the relationship between performance on a comprehensive battery of neuropsychological tests and the presence of clinical, subclinical or no cardiovascular disease in an elderly community-dwelling population. The results confirm previous reports of significant associations of age, education and gender with test performance. When performance was examined controlling for these variables, significant associations of disease group were seen with five measures emphasizing speed of performance; Parts A and B of the Trail Making Test, the WAIS-R Digit Symbol and Block Design subtests and category verbal fluency. These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels. Copyright (C) 2000 S. Karger AG, Basel.

KW - Aging

KW - Cardiovascular disease

KW - Cognitive functioning

UR - http://www.scopus.com/inward/record.url?scp=0033772782&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033772782&partnerID=8YFLogxK

U2 - 10.1159/000026270

DO - 10.1159/000026270

M3 - Article

C2 - 11060505

AN - SCOPUS:0033772782

SN - 0251-5350

VL - 19

SP - 312

EP - 319

JO - Neuroepidemiology

JF - Neuroepidemiology

IS - 6

ER -

Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this