Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study

Judith Saxton, Graham Ratcliff, Anne Newman, Steven Belle, Linda Fried, John Yee, Lewis Kuller

Research output: Contribution to journalArticle

Abstract

The purpose of the present study was to investigate the relationship between performance on a comprehensive battery of neuropsychological tests and the presence of clinical, subclinical or no cardiovascular disease in an elderly community-dwelling population. The results confirm previous reports of significant associations of age, education and gender with test performance. When performance was examined controlling for these variables, significant associations of disease group were seen with five measures emphasizing speed of performance; Parts A and B of the Trail Making Test, the WAIS-R Digit Symbol and Block Design subtests and category verbal fluency. These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)312-319
Number of pages8
JournalNeuroepidemiology
Volume19
Issue number6
DOIs
StatePublished - 2000

Keywords

  • Aging
  • Cardiovascular disease
  • Cognitive functioning

ASJC Scopus subject areas

  • Epidemiology
  • Clinical Neurology

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