Cognitive Loss and Recovery in Long-term Alcohol Abusers

Jason Brandt, Nelson Butters, Christopher Ryan, Roger Bayog

Research output: Contribution to journalArticle

Abstract

The nature of the memory and visuospatial defects associated with chronic alcoholism, and the recovery of these functions, were investigated in a large group of alcoholic men and well-matched nonalcoholic controls. Both young and old alcoholics displayed significant impairments on tasks requiring the learning of novel associations and the holding of information in memory over longer delay intervals. The recovery of cognitive skills was found to depend on the length of abstinence and the particular behavioral functions examined. Whereas psychomotor skills and short-term memory improved significantly with prolonged abstinence, long-term memory was impaired even after seven years of continuous sobriety. We propose that recovery of short-term memory reflects reestablishment of cortical functioning, while the persistent long-term memory defect indicates more permanent damage to diencephalic structures.

Original languageEnglish (US)
Pages (from-to)435-442
Number of pages8
JournalArchives of general psychiatry
Volume40
Issue number4
DOIs
StatePublished - Apr 1983

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health

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