Cognitive deficits in patients with chronic fatigue syndrome

Barbara Marcel; Anthony L. Komaroff; Laura R. Fagioli; R. James Kornish; Marilyn S. Albert

doi:10.1016/0006-3223(95)00422-X

Cognitive deficits in patients with chronic fatigue syndrome

Barbara Marcel, Anthony L. Komaroff, Laura R. Fagioli, R. James Kornish, Marilyn S. Albert

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

Twenty-nine subjects with chronic fatigue syndrome (CFS) and 25 healthy control subjects were administered a lengthy neuropsychological battery that included standard neuropsychological tests and a computerized set of tasks that spanned the same areas of ability. The primary significant differences between patients and controls were found on tests of learning and memory. These differences remained when the degree of psychiatric symptomatology in the subjects was covaried. Patients on and of psychoactive medications did not differ in their performance an these tasks. These results suggest that at least a subset of CFS patients may experience significant impairments in learning and memory.

Original language	English (US)
Pages (from-to)	535-541
Number of pages	7
Journal	Biological psychiatry
Volume	40
Issue number	6
DOIs	https://doi.org/10.1016/0006-3223(95)00422-X
State	Published - Sep 15 1996
Externally published	Yes

Keywords

CFS
Cognition
ME
Memory
Psychiatric symptoms

ASJC Scopus subject areas

Biological Psychiatry

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10.1016/0006-3223(95)00422-X

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title = "Cognitive deficits in patients with chronic fatigue syndrome",

abstract = "Twenty-nine subjects with chronic fatigue syndrome (CFS) and 25 healthy control subjects were administered a lengthy neuropsychological battery that included standard neuropsychological tests and a computerized set of tasks that spanned the same areas of ability. The primary significant differences between patients and controls were found on tests of learning and memory. These differences remained when the degree of psychiatric symptomatology in the subjects was covaried. Patients on and of psychoactive medications did not differ in their performance an these tasks. These results suggest that at least a subset of CFS patients may experience significant impairments in learning and memory.",

keywords = "CFS, Cognition, ME, Memory, Psychiatric symptoms",

author = "Barbara Marcel and Komaroff, {Anthony L.} and Fagioli, {Laura R.} and Kornish, {R. James} and Albert, {Marilyn S.}",

note = "Funding Information: The study was conducted by the CFS Cooperative Research Center at Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, which was established by funding from the National Institutes of Health.",

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T1 - Cognitive deficits in patients with chronic fatigue syndrome

AU - Marcel, Barbara

AU - Komaroff, Anthony L.

AU - Fagioli, Laura R.

AU - Kornish, R. James

AU - Albert, Marilyn S.

N1 - Funding Information: The study was conducted by the CFS Cooperative Research Center at Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, which was established by funding from the National Institutes of Health.

PY - 1996/9/15

Y1 - 1996/9/15

N2 - Twenty-nine subjects with chronic fatigue syndrome (CFS) and 25 healthy control subjects were administered a lengthy neuropsychological battery that included standard neuropsychological tests and a computerized set of tasks that spanned the same areas of ability. The primary significant differences between patients and controls were found on tests of learning and memory. These differences remained when the degree of psychiatric symptomatology in the subjects was covaried. Patients on and of psychoactive medications did not differ in their performance an these tasks. These results suggest that at least a subset of CFS patients may experience significant impairments in learning and memory.

AB - Twenty-nine subjects with chronic fatigue syndrome (CFS) and 25 healthy control subjects were administered a lengthy neuropsychological battery that included standard neuropsychological tests and a computerized set of tasks that spanned the same areas of ability. The primary significant differences between patients and controls were found on tests of learning and memory. These differences remained when the degree of psychiatric symptomatology in the subjects was covaried. Patients on and of psychoactive medications did not differ in their performance an these tasks. These results suggest that at least a subset of CFS patients may experience significant impairments in learning and memory.

KW - CFS

KW - Cognition

KW - ME

KW - Memory

KW - Psychiatric symptoms

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JO - Biological Psychiatry

JF - Biological Psychiatry

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Cognitive deficits in patients with chronic fatigue syndrome

Abstract

Keywords

ASJC Scopus subject areas

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