Coding of microsaccades in three-dimensional space by premotor saccadic neurons

Marion R. van Horn, Kathleen E. Cullen

Research output: Contribution to journalArticlepeer-review

Abstract

Microsaccades are small, involuntary eye movements that are produced during fixation. While accurate visual perception requires precise binocular coordination during fixation, previous studies of the neural control of microsaccades measured the movement of one eye only. Here we show how premotor saccadic neurons control these small fixational eye movements in three-dimensional space. Microsaccadic eye movements, produced by monkeys trained to fixate targets presented at different depths, were similarly distributed in three-dimensional space during both near and far viewing. Single unit recordings of the neural activity of premotor neurons further revealed that the brainstem saccadic circuitry controls these minute disconjugate shifts of gaze by preferentially encoding the dynamic movement of an individual eye (i.e., integrated control of conjugate and vergence motion). These findings challenge the traditional notion that microsaccades are strictly conjugate and have important implications for studies that use microsaccades to evaluate visual and attentional processing, as well as certain neurological disorders.

Original languageEnglish (US)
Pages (from-to)1974-1980
Number of pages7
JournalJournal of Neuroscience
Volume32
Issue number6
DOIs
StatePublished - Feb 8 2012
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Coding of microsaccades in three-dimensional space by premotor saccadic neurons'. Together they form a unique fingerprint.

Cite this