Cochlear wall titanium implants for auditory nerve stimulation.

J. K. Niparko, B. E. Pfingst, C. Johansson, P. R. Kileny, J. L. Kemink, A. Tjellström

Research output: Contribution to journalArticle

Abstract

Genetically deaf dalmatian dogs and ototoxically deafened macaque monkeys were implanted with electrodes housed in cochlear wall titanium implants to assess long-term stability, tolerance, and performance. Short-term human implantation, followed by trials of stimulation, was performed in 4 unilaterally deaf patients. In the dog experiments, cochlear wall electrode stimulation produced consistent electrophysiologic thresholds that were higher, by approximately 6 dB, than those obtained with bipolar scala tympani stimulation. Clinical testing revealed electrically evoked middle latency response, auditory brain stem response, and/or behavioral detection responses in 3 of 4 patients, at levels below those for facial nerve activation and pain sensation. Electrode place discrimination studies, with controls for loudness cues, revealed near-perfect discrimination in a monkey subject. Eleven of the 12 animal implants were found to be rigidly fixed in the cochlear bone, with direct contract between bone and implant over 8% to 23% of the implant surface for the 6 implants examined in detail. These results suggest that long-term fixation of titanium cochlear wall implants occurs by virtue of intimate implant-bone contact in restricted areas. This approach to prosthetic stimulation demonstrates encouraging performance characteristics in achieving auditory activation.

Original languageEnglish (US)
Pages (from-to)447-454
Number of pages8
JournalAnnals of Otology, Rhinology and Laryngology
Volume102
Issue number6
StatePublished - Jun 1993
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology

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  • Cite this

    Niparko, J. K., Pfingst, B. E., Johansson, C., Kileny, P. R., Kemink, J. L., & Tjellström, A. (1993). Cochlear wall titanium implants for auditory nerve stimulation. Annals of Otology, Rhinology and Laryngology, 102(6), 447-454.