Cocaine colitis - Is this a new syndrome?

Rhonda Fishel, Gary Hamamoto, Adrian Barbul, Violet Jiji, Gershon Efron

Research output: Contribution to journalArticle

Abstract

An unusual case of colitis in a 37-year-old cocaine addict is described. The patient presented with right-sided abdominal pain and diarrhea exacerbated by his use of cocaine. Significant antibiotic ingestion was denied. At laparotomy, an edematous cecum and ascending colon were found, the cut surface of which revealed diffuse superficial ulcerations and yellowish fibrinous material. Microscopic examination demonstrated findings consistent with pseudomembranous colitis with an ischemic component. A mechanism involving chathecholamine-induced mucosal ischemia is postulated to explain the findings seen in this patient.

Original languageEnglish (US)
Pages (from-to)264-266
Number of pages3
JournalDiseases of the Colon & Rectum
Volume28
Issue number4
DOIs
StatePublished - Apr 1 1985

Keywords

  • Catecholamines
  • Cocaine
  • Diarrhea
  • Ischemic colitis
  • Pseudomembranous colitis

ASJC Scopus subject areas

  • Gastroenterology

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