Clozapine: Acquittal of the usual suspect

Tanja Schmitz-Hübsch, Thomas E. Schläepfer, Jens Westheide, Marcus Von Falkenhausen, Deirdre Cooper-Mahkorn, Wolfgang Maier, Kai Uwe Khn

Research output: Contribution to journalArticlepeer-review


This report concerns the case of a 29-year-old male patient suffering from severe psychotic illness who had been satisfactorily treated with clozapine for 4 months. Clozapine had also been successfully administered during a psychotic episode 5 years previously. Though symptoms of psychosis were successfully controlled following the most recent psychotic episode, a medical consultation assessed that exacerbation of pancreatitis warranted discontinuation of the current antipsychotic treatment regime. Following a series of unsuccessful courses of neuroleptic medication, a magnetic resonance cholangiopancreaticography (MRCP) revealed marked cholecystolithiasis suggesting a biliary pancreatitis. Clozapine treatment was readministered following cholecystectomy. After 4 weeks of antipsychotic treatment the patient was discharged from hospital on clozapine monotherapy.

Original languageEnglish (US)
Pages (from-to)981-984
Number of pages4
JournalWorld Journal of Biological Psychiatry
Issue number4 PART 3
StatePublished - Dec 1 2009


  • Cholecystolithiasis
  • Clozapine
  • Pancreatitis
  • Side effects

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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