Cloud-scale RNA-sequencing differential expression analysis with Myrna.

Research output: Contribution to journalArticlepeer-review

Abstract

As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the analysis of publicly available data sets and assess the goodness of fit of standard statistical models. Myrna is available from http://bowtie-bio.sf.net/myrna.

Original languageEnglish (US)
Pages (from-to)R83
JournalGenome biology
Volume11
Issue number8
DOIs
StatePublished - 2010
Externally publishedYes

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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