TY - JOUR
T1 - Clostridium difficile infection in pediatric inflammatory bowel disease
AU - Hourigan, Suchitra K.
AU - Sears, Cynthia L.
AU - Oliva-Hemker, Maria
N1 - Publisher Copyright:
© 2015 Crohn's & Colitis Foundation of America, Inc.
PY - 2016/3/9
Y1 - 2016/3/9
N2 - Children with inflammatory bowel disease (IBD) are disproportionately susceptible to Clostridium difficile infection (CDI) and the incidence is increasing. There has also been growing recognition of asymptomatic C. difficile colonization in pediatric IBD, which can sometimes be very difficult to distinguish from symptomatic C. difficile-associated disease in this population. In this study, we discuss the current knowledge of C. difficile infection in children with IBD, reviewing epidemiology, risk factors, and outcomes that often differ from the adult IBD population, and discuss the complexities and dilemmas of diagnosing and treating CDI in pediatric IBD.
AB - Children with inflammatory bowel disease (IBD) are disproportionately susceptible to Clostridium difficile infection (CDI) and the incidence is increasing. There has also been growing recognition of asymptomatic C. difficile colonization in pediatric IBD, which can sometimes be very difficult to distinguish from symptomatic C. difficile-associated disease in this population. In this study, we discuss the current knowledge of C. difficile infection in children with IBD, reviewing epidemiology, risk factors, and outcomes that often differ from the adult IBD population, and discuss the complexities and dilemmas of diagnosing and treating CDI in pediatric IBD.
KW - Clostridium difficile infection
KW - children
KW - inflammatory bowel disease
KW - pediatric
UR - http://www.scopus.com/inward/record.url?scp=84962232874&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84962232874&partnerID=8YFLogxK
U2 - 10.1097/MIB.0000000000000666
DO - 10.1097/MIB.0000000000000666
M3 - Review article
C2 - 26689599
AN - SCOPUS:84962232874
SN - 1078-0998
VL - 22
SP - 1020
EP - 1025
JO - Inflammatory Bowel Diseases
JF - Inflammatory Bowel Diseases
IS - 4
ER -