Clostridium difficile: an under-recognized cause of reactive arthritis?

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Reactive arthritis usually presents as a sterile, inflammatory, asymmetric oligoarthritis, affecting large lower extremity joints. Extra-articular features (conjunctivitis, uveitis, enthesopathy, urethritis, balanitis, keratoderma blenorrhagicum) may occur. Common causes of enteric reactive arthritis are preceding infections attributable to Salmonella, Shigella, Campylobacter, and Yersinia. In contrast, Clostridium difficile is an uncommon cause of reactive arthritis, with only approximately 40 reported cases. We describe a patient with an intense additive, asymmetric oligoarthritis after an antecedent C. difficile infection. The potential contribution of C. difficile to more insidious cases of undifferentiated oligoarthritis is discussed, with emphasis on corresponding therapeutic interventions.

Original languageEnglish (US)
Pages (from-to)253-255
Number of pages3
JournalClinical rheumatology
Issue number2
StatePublished - Feb 2008

ASJC Scopus subject areas

  • Rheumatology


Dive into the research topics of 'Clostridium difficile: an under-recognized cause of reactive arthritis?'. Together they form a unique fingerprint.

Cite this