Clomipramine ameliorates adventitious movements and compulsions in prepubertal boys with autistic disorder and severe mental retardation

James R. Brasic; J. Y. Barnett; D. Kaplan; B. B. Sheitman; P. Aisemberg; R. T. Lafargue; S. Kowalik; A. Clark; M. O. Tsaltas; J. G. Young

doi:10.1212/wnl.44.7.1309

Clomipramine ameliorates adventitious movements and compulsions in prepubertal boys with autistic disorder and severe mental retardation

James R. Brasic, J. Y. Barnett, D. Kaplan, B. B. Sheitman, P. Aisemberg, R. T. Lafargue, S. Kowalik, A. Clark, M. O. Tsaltas, J. G. Young

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

In an open, nonblind clinical trial, clomipramine reduced adventitious movementsand compulsions in five previously medicated prepubertal boys with autistic disorder andsevere mental retardation. Poorly adapted rating scales, interrater variability, subjectheterogeneity, different treatment histories, and environmental stresses confounded the assessment of treatment effects.

Original language	English (US)
Pages (from-to)	1309-1312
Number of pages	4
Journal	Neurology
Volume	44
Issue number	7
DOIs	https://doi.org/10.1212/wnl.44.7.1309
State	Published - Jul 1994
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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title = "Clomipramine ameliorates adventitious movements and compulsions in prepubertal boys with autistic disorder and severe mental retardation",

abstract = "In an open, nonblind clinical trial, clomipramine reduced adventitious movementsand compulsions in five previously medicated prepubertal boys with autistic disorder andsevere mental retardation. Poorly adapted rating scales, interrater variability, subjectheterogeneity, different treatment histories, and environmental stresses confounded the assessment of treatment effects.",

author = "Brasic, {James R.} and Barnett, {J. Y.} and D. Kaplan and Sheitman, {B. B.} and P. Aisemberg and Lafargue, {R. T.} and S. Kowalik and A. Clark and Tsaltas, {M. O.} and Young, {J. G.}",

year = "1994",

month = jul,

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AU - Brasic, James R.

AU - Barnett, J. Y.

AU - Kaplan, D.

AU - Sheitman, B. B.

AU - Aisemberg, P.

AU - Lafargue, R. T.

AU - Kowalik, S.

AU - Clark, A.

AU - Tsaltas, M. O.

AU - Young, J. G.

PY - 1994/7

Y1 - 1994/7

N2 - In an open, nonblind clinical trial, clomipramine reduced adventitious movementsand compulsions in five previously medicated prepubertal boys with autistic disorder andsevere mental retardation. Poorly adapted rating scales, interrater variability, subjectheterogeneity, different treatment histories, and environmental stresses confounded the assessment of treatment effects.

AB - In an open, nonblind clinical trial, clomipramine reduced adventitious movementsand compulsions in five previously medicated prepubertal boys with autistic disorder andsevere mental retardation. Poorly adapted rating scales, interrater variability, subjectheterogeneity, different treatment histories, and environmental stresses confounded the assessment of treatment effects.

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Clomipramine ameliorates adventitious movements and compulsions in prepubertal boys with autistic disorder and severe mental retardation

Abstract

ASJC Scopus subject areas

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