TY - JOUR
T1 - Clinicoradiological correlation of scoliosis in children with Jarcho-Levin and Escobar syndromes
T2 - associated “flat bone or wing-like” imaging findings
AU - Bosemani, Thangamadhan
AU - Poretti, Andrea
AU - Benson, Jane E.
AU - Meyer-Heim, Andreas
AU - Huisman, Thierry A.G.M.
N1 - Publisher Copyright:
© 2014, Springer-Verlag Berlin Heidelberg.
PY - 2014/9/12
Y1 - 2014/9/12
N2 - Congenital or early onset scoliosis may be the lead clinical feature in several rare syndromes. In this paper, we present the imaging findings in two children with early onset scoliosis related to the Jarcho-Levin and Escobar syndromes and an osseous plate or wing-like bar extending along the posterior elements of the spine on computed tomography. The clinical phenotypes in these syndromes are variable. A thorough clinical evaluation with imaging correlation is essential. The recognition of underlying spinal anomalies is essential in planning treatment and estimating prognosis. In young children with progressive scoliosis, cross-sectional imaging plays a major role in the diagnostic work-up. Conclusion: Congenital scoliosis requires a comprehensive clinical evaluation and imaging work-up. The presence of an osseous plate or wing-like fusion of posterior elements of the spine may suggest the diagnosis of Jarcho-Levin and Escobar syndromes.
AB - Congenital or early onset scoliosis may be the lead clinical feature in several rare syndromes. In this paper, we present the imaging findings in two children with early onset scoliosis related to the Jarcho-Levin and Escobar syndromes and an osseous plate or wing-like bar extending along the posterior elements of the spine on computed tomography. The clinical phenotypes in these syndromes are variable. A thorough clinical evaluation with imaging correlation is essential. The recognition of underlying spinal anomalies is essential in planning treatment and estimating prognosis. In young children with progressive scoliosis, cross-sectional imaging plays a major role in the diagnostic work-up. Conclusion: Congenital scoliosis requires a comprehensive clinical evaluation and imaging work-up. The presence of an osseous plate or wing-like fusion of posterior elements of the spine may suggest the diagnosis of Jarcho-Levin and Escobar syndromes.
KW - CT
KW - Escobar syndrome
KW - Jarcho-Levin syndrome
KW - MRI
KW - Scoliosis
KW - Spine anomalies
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U2 - 10.1007/s00431-014-2324-4
DO - 10.1007/s00431-014-2324-4
M3 - Article
C2 - 24791932
AN - SCOPUS:84918815335
SN - 0340-6199
VL - 173
SP - 1377
EP - 1380
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
IS - 10
ER -