Clinicopathologic correlation of lipidization and detachment of the retinal pigment epithelium

Fadi El Baba; W. Richard Green; Jay Fleischmann; Daniel Finkelstein; Zenaida C. de la Cruz

doi:10.1016/0002-9394(86)90948-7

Clinicopathologic correlation of lipidization and detachment of the retinal pigment epithelium

Fadi El Baba, W. Richard Green, Jay Fleischmann, Daniel Finkelstein, Zenaida C. de la Cruz

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A 49-year-old woman had a few small drusen-like lesions and one larger area of depigmentation in the right fundus. The pinpoint lesions corresponded to single enlarged retinal pigment epithelial cells with lipid accumulation and the larger area represented a small, localized retinal pigment epithelial detachment (soft druse). Lipoidal degeneration of individual retinal pigment epithelial cells may be a mechanism of nodular drusen formation. The soft druse was associated with thickening of the basement membrane of the retinal pigment epithelium.

Original language	English (US)
Pages (from-to)	576-583
Number of pages	8
Journal	American journal of ophthalmology
Volume	101
Issue number	5
DOIs	https://doi.org/10.1016/0002-9394(86)90948-7
State	Published - May 15 1986
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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10.1016/0002-9394(86)90948-7

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title = "Clinicopathologic correlation of lipidization and detachment of the retinal pigment epithelium",

abstract = "A 49-year-old woman had a few small drusen-like lesions and one larger area of depigmentation in the right fundus. The pinpoint lesions corresponded to single enlarged retinal pigment epithelial cells with lipid accumulation and the larger area represented a small, localized retinal pigment epithelial detachment (soft druse). Lipoidal degeneration of individual retinal pigment epithelial cells may be a mechanism of nodular drusen formation. The soft druse was associated with thickening of the basement membrane of the retinal pigment epithelium.",

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AU - El Baba, Fadi

AU - Green, W. Richard

AU - Fleischmann, Jay

AU - Finkelstein, Daniel

AU - de la Cruz, Zenaida C.

PY - 1986/5/15

Y1 - 1986/5/15

N2 - A 49-year-old woman had a few small drusen-like lesions and one larger area of depigmentation in the right fundus. The pinpoint lesions corresponded to single enlarged retinal pigment epithelial cells with lipid accumulation and the larger area represented a small, localized retinal pigment epithelial detachment (soft druse). Lipoidal degeneration of individual retinal pigment epithelial cells may be a mechanism of nodular drusen formation. The soft druse was associated with thickening of the basement membrane of the retinal pigment epithelium.

AB - A 49-year-old woman had a few small drusen-like lesions and one larger area of depigmentation in the right fundus. The pinpoint lesions corresponded to single enlarged retinal pigment epithelial cells with lipid accumulation and the larger area represented a small, localized retinal pigment epithelial detachment (soft druse). Lipoidal degeneration of individual retinal pigment epithelial cells may be a mechanism of nodular drusen formation. The soft druse was associated with thickening of the basement membrane of the retinal pigment epithelium.

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ER -

Clinicopathologic correlation of lipidization and detachment of the retinal pigment epithelium

Abstract

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