Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

M. E. Smith; L. A. Stone; P. S. Albert; J. A. Frank; R. Martin; M. Armstrong; H. Maloni; D. E. McFarlin; H. F. McFarland

Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

M. E. Smith, L. A. Stone, P. S. Albert, J. A. Frank, R. Martin, M. Armstrong, H. Maloni, D. E. McFarlin, H. F. McFarland

Research output: Contribution to journal › Article › peer-review

244 Scopus citations

Abstract

It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS]

Original language	English (US)
Pages (from-to)	480-489
Number of pages	10
Journal	Annals of Neurology
Volume	33
Issue number	5
State	Published - May 1993
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience

Cite this

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title = "Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions",

abstract = "It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS] ",

author = "Smith, {M. E.} and Stone, {L. A.} and Albert, {P. S.} and Frank, {J. A.} and R. Martin and M. Armstrong and H. Maloni and McFarlin, {D. E.} and McFarland, {H. F.}",

year = "1993",

month = may,

language = "English (US)",

volume = "33",

pages = "480--489",

journal = "Annals of Neurology",

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T1 - Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

AU - Smith, M. E.

AU - Stone, L. A.

AU - Albert, P. S.

AU - Frank, J. A.

AU - Martin, R.

AU - Armstrong, M.

AU - Maloni, H.

AU - McFarlin, D. E.

AU - McFarland, H. F.

PY - 1993/5

Y1 - 1993/5

N2 - It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS]

AB - It is now well established that clinically stable patients with relapsing-remitting multiple sclerosis have ongoing disease activity when evaluated by serial gadolinium-enhanced (Gd-DTPA) magnetic resonance imaging (MRI) scans. Despite this, the relationship between clinical disease and MRI lesions, though suspected, has not been extensively documented. The relationship between Gd-DTPA MRI lesions and clinical disease was examined in this study of 9 patients with mild relapsing-remitting multiple sclerosis (Expanded Disability Status Scale [EDSS]

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AN - SCOPUS:0027225525

SN - 0364-5134

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SP - 480

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JO - Annals of Neurology

JF - Annals of Neurology

IS - 5

ER -

Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions

Abstract

ASJC Scopus subject areas

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